Cell Membrane Organization and Dynamics
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| Knowledge area Biophysics |
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| PI: Adai Colom | Co-PI: | |
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Members Adai Colom / Marián Alonso / Andrea Merino |
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Keywords Cell membrane biophysics, protein dynamics, HS-AFM, FLIM |
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Description We aim to understand the role of membrane mechanics and protein dynamic involve in different cell process, especially, we are focus on immunological synapse, viral infection and ebriogenesis. We use a wide range of systems (in-vitro to embryos) and technics, particularly HS-AFM and Fast-FLIM. Objectives: 1-A new approach to study the mechanochemistry of cellular processes at high spatio-tempral resolution. 2-Measure the forces involved during embryogenesis and tissue-tissue communication. 3-Insight on the spatiotemporal organization and mechanics of protein complexes during the formation of the immunological synapse and viral infection. 4- Apply our technology, especially FAST-FLIM, as a fast and cheap diagnosis tool in infection and tumorigenesis. |
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