University of the Basque Country University of the Basque Country

Cabecera Cofund

Advanced Manufacturing Research Fellowship Programme Adagio

Advanced ManufacturIng Research Fellowship Programme in the Basque - New Aquitaine Region (ADAGIO)

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Asset Publisher

Host Research Group

ES4_Microfluidics Cluster UPV/EHU_Lourdes Basabe Desmonts

Lourdes Basabe Desmonts

0034 945014538

lourdes.basabe@ehu.eus

https://www.ehu.eus/en/web/microfluidics

Group description

 

The Microfluidics Cluster UPV/EHU is a strategic alliance between two research teams working on Micro- and Nanotechnologies for Lab-on-a-Chip applications at the University of the Basque Country.

We focus on applied and translational research on micro- and nanotechnologies. Through the combination of microfluidics, sensors and actuators, we develop Integrated Microsystems with applications in biomedical diagnostics, environmental analysis, chemistry, sport science, biology and medicine.

We are a multidisciplinary team comprised by chemists, biologists and engineers, in close collaboration with sport and environmental scientists, medical doctors, and industry.

Lines of Research

Research Line 1. Microfluidics.

1- Developing and characterizing novel microfabrication techniques, to produce microfluidic architectures and microfluidic components, in paper, plastics, or hybrid architectures.
2- Developing self-powered microfluidic networks.
3- Developing micro pumps for lab-on-a-chip applications.
4- Developing integrated sensors for lab-on-a-chip applications.

Research Line 2. Smart materials for sensing and actuation.

1- Integration of plasmonic nanosensors based on metal nanoparticles, biosensors based on antibody immobilization and other novel optical sensing strategies.

2- Stimuli-responsive materials able to undergo volumetric changes in response to physical and chemical changes in their local environment.

3- Integration of valves in microfluidic devices for flow control.

4- Integration of smart materials in microfluidic devices for sensing applications.

5- Magnetic material, actuators.

Research Line 3. Surface engineering.

1- Modification of chemical and topographic properties of surfaces.

2- Patterning of plastic, glass and paper substrates with chemicals and nanoparticles.

Research Line 4. Microsystem integration.

We are developing specific workflow designs to be able to integrate the different components and protocols developed in our group to produce functional microsystems.

1- Devices for nucleic acid purification and analysis.

2- Water analysis devices.

3- Disposable, wearable devices for sweat analysis.

4- Microfluidic platform for cell culture and monitoring.

Keywords

  • Lab-on-a-Chip
  • Point of care devices
  • Microfluidics
  • Smart Materials
  • 3D printing
  • Devices
  • Microtechnology
  • Surface Engineer
  • Nanotechnology
  • Chemistry

Team Description

  • Lourdes Basabe-Desmonts (Principal Investigator)

    ORCID: 0000-0002-6638-7370

  • Fernando Benito López (Co-Principal Investigator)

    ORCID: 0000-0003-0699-5507

  • Janire Saez Castaño (Post-Doctoral Researcher)

    ORCID: 0000-0002-9246-0818

  • Daniel Patko (Post-Doctoral Researcher)

    ORCID: 0000-0002-3553-2213

Projects

  • DNASURF

    Pl: Dr. Eimer Tuite, Newcastle University, UK

    Funding Agency*: EU; H2020-MSCA-RISE

    Ongoing: yes

    Project reference: H2020-MSCA-RISE17/03

  • MAMI: Magnetics and Microhydrodynamics - from guided transport to delivery

    Pl: Prof. Bernard Doudin, Centre National de la Recherche Scientifique CNRS, France

    Funding Agency*: EU; 2020-MSCA-ITN-ETN

    Ongoing: no

    Project reference: H2020-MSCA-ITN14/10

  • NAPES: Next Generation Analytical Platforms for Environmental Sensing

    Pl: Dr. Dermot Diamond and Dr. Fernando Benito López at CIC MicroGUNE/UPV/EHU

    Funding Agency*: EU; FP7

    Ongoing: no

    Project reference: 7PM-COOP-SCP13/07

  • Microfluidics & Biomics Cluster UPV/EHU (IT1271-19)

    Pl: Prof. Lourdes Basabe Desmonts,

    Funding Agency*: RE; Basque Government

    Ongoing: yes

    Project reference: GIC21/107

  • Micro and nanotechnology: integration strategies for the development of microsystems for chemical and cellular analysis (ChemCellTec)

    Pl: Prof. Lourdes Basabe Desmonts and Assoc. Prof. Fernando Benito López

    Funding Agency*: NAT; Spanish Government

    Ongoing: yes

    Project reference: MINECOG20/P02

* INT - International EU - European NAT - National RE - Regional

Publications

  • V. Nasirimarekani, F. Benito-Lopez, L. Basabe-Desmonts, = Tunable Superparamagnetic Ring (tSPRing) for Droplet Manipulation, Adv. Funct. Mater, 2021
    https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.202100178

  • Y. Alvarez-Braña, J. Etxeberria-Elezgarai, L. Ruiz de Larrinaga-Vicente, F. Benito-Lopez, L. Basabe-Desmonts, = Modular Micropumps Fabricated by 3D Printed Technologies for Polymeric Microfluidic Device Applications, Sens. Actuators B, 2021
    https://doi.org/10.1016/j.snb.2021.129991

  • E. Azuaje-Hualde, M. Rosique, A. Calatayud-Sanchez, F. Benito-Lopez, M. M. de Pancorbo, L. Basabe-Desmont, = Continuous Monitoring of Cell Transfection Efficiency with Micropatterned Substrates, Biotechnol. Bioeng, 2021
    https://doi.org/10.1002/bit.27783

  • A. Ortega-Gomez, J. Barroso, A. Calatayud-Sanchez, J. Zubia, F. Benito-Lopez, L. Basabe-Desmonts, J. Villatoro, = Cytochrome c detection by plasmonic nanospectroscopy on optical fiber facets, Sens. Actuators B, 2021
    https://doi.org/10.1002/bit.27783

  • A. Ortega-Gomez, J. Barroso, A. Calatayud-Sanchez, J. Zubia, F. Benito-Lopez, L. Basabe-Desmonts, J. Villatoro, = Cytochrome c detection by plasmonic nanospectroscopy on optical fiber facets, Sens. Actuators B, 2021
    https://doi.org/10.1016/j.snb.2020.129358

  • J. Etxeberria-Elezgarai, Y. Alvarez-Braña, R. Garoz-Sanchez, F. Benito-Lopez, L. Basabe-Desmonts, = Large Volume Self-powered Disposable Microfluidics by the Integration of Modular Polymer Micropumps with Plastic Microfluidic Cartridges, Ind. Eng. Chem. Res, 2020
    https://doi.org/10.1021/acs.iecr.0c03398

Research Lines

ADVANCED MATERIALS AND PROCESSES

Smart materials and optofluidics

  • Integration of plasmonic nanosensors based on metal nanoparticles, biosensors based on antibody immobilization and other novel optical sensing strategies.

Smart materials for actuation

  • Stimuli-responsive materials able to undergo volumetric changes in response to physical and chemical changes in their local environment.
  • Integration of valves in microfluidic devices for flow control.
  • Magnetic material, actuators.

Smart materials for sensing

3D scaffolds for cell culture and monitoring

Magnetic materials as sensors.

Bioelectronics

 

INTELLIGENT, FLEXIBLE & EFFICIENT PRODUCTION SYSTEMS

Microfluidic platform for cell culture and monitoring.

  • Design, fabrication and performance of microfluidic devices and components for the fundamental studies of biological processes.
  • Organ-on-a-chip devices.
  • 3D scaffolds for cell culture and monitoring

Disposable, wearable devices for biofluids analysis

  • Provide to the society and the researchers with analytical devices able to integrate and to automate a sequence of steps: from sample preparation, analysis to results reporting.

Microfluidic devices for environmental analysis

  • Develop Microfluidic devices, components and systems for environmental analysis at the point of need.

SUSTAINABLE MANUFACTURING

Microfluidic device fabrication, 3D printing techniques

Develop new methodologies for the fabrication of Microfluidic devices and components for industry.

Cross-border Collaboration (if any)

Not at the moment, Looking forward to start new collaborations within this project frame