Research Lines

Line 1. Multifunctional laser dyes based on BODIPY

The BODIPYs stand out for their great synthetic versatility; its chromophoric nucleus is reactive for numerous synthetic routes, which allows functionalizing selectively. Therefore, the photophysical properties of BODIPY can be modulated through the substitution pattern, which allows the development of dyes with properties on demand and with multiple applications.

1.1. Fluorescent probes in bioimaging

1.2.   BODIPYs capable of absorbing two photons

1.3. Molecular sensors

1.4. Multicomromorphic dyes as molecular antennas

1.5.  BODIPYs con actividad quiroóptica.

1.4. BODIPYs with chiro-optical activity.


Line 2.  Photosensitizers for the generation of singlet oxygen in photodynamic therapy

The BODIPYs have focused great interest as photosensitizers; through its functionalization, highly fluorescent dyes can be transformed into "dark" dyes with a high population of their triplet state. In addition, their photophysics, which are not very sensitive to environmental conditions, high lipophilicity and high resistance to photodegradation, make them ideal candidates for PDT.

2.1. New photosensitizers based on the BODIPY structure through appropriate functionalization or by binding to organometallic derivatives.

2.2. Nanoparticles as hosts of the photosensitizers for their implantation in photodynamic therapy and teragnosis.


Line 3. Multifunctional photoactive materials

The confinement of fluorescent dyes in organic and inorganic supports increases its photo and thermostability. In addition, the environmental rigidity infers to the fluorophore a constricted environment in such a way that it limits its molecular movement, avoids the formation of non-fluorescent aggregates and induces a preferential orientation of the dye, giving rise to very ordered materials. Therefore, these materials stand out for a high fluorescent signal and are susceptible to be applied in various scientific fields.

3.1. Latex microparticles

3.2. Porous hybrid materials

3.3. Occlusion of dyes in MOFs

Line 4. Atomic simulation of energy efficient cementitious materials

Using methods of atomistic simulation in the study of cement and its components is wanted to achieve a fundamental knowledge of the physics of it to make it more efficient from the energy point of view but without losing its current mechanical properties.

4.1. Hydration and kinetics of cementitious minerals4.1.  Hydration and kinetics of cementitious minerals

4.2. Structure and growth of the C-S-H gel

4.3. Performance of C-S-H gel and cement for high performance applications 4.4. Organic-inorganic interaction (superplasticizers)


Pass Subject

  •  Photophysics of Rhodamines in Polymeric Solid Matrix.   (1995-2002)
  • Anisotropic Study of Dyes on Clay Thin-Films by Polarized Light. (1997-2003)
  • Cis-trans Photoisomerization of Azobenzene Derivatives in Laminar Materials. (1999 – 2000).
  • Spectroscopy Study of Dyes Adsorbed on Clay Aqueous Suspensions. (1990-2001).
  • Photophysics of Laser-Dyes (Rhodamins and 7-aminocoumarins) in Solution. Effect of the Molecular Structure and Solvent. (1988-1994).
  • Aggregation of Rhodamines in Solution. Effect on the Fluorescent Capacity. (1980-1989).