Description and contextualization of the subject

Analytical chemistry is an integral and essential component in many diverse areas, such as electrochemical technology, medical technology, pharmaceutical industry, etc. The principles of Analytical Chemistry are routinely applied in these areas for quality control, research and development work. Analytical chemistry studies the separation, identification and quantification of the chemical components of natural and artificial materials. This course will provide the student with:

- a theoretical foundation on the principles of analytical methods and important techniques of classical and instrumental analysis.

- skills on measurements and errors in chemical analysis, calculation, and interpretation of results.

- knowledge of different spectroscopic techniques and separation methods.

Temary

1. Statistical evaluation of Analytical data

Statistics is a valuable tool in the laboratory to determine the number of measurements required, significant difference in a sample analysed by different methods, difference in precision, detection limits, treating calibration data, establish the uncertainty associated with the measurement, etc.

2. Principles of Gravimetric & Volumetric analysis

Gravimetric methods of analysis are based on the measurement of mass. The two gravimetric methods are precipitation and volatilization methods.

Volumetric analysis, also called titrimetic analysis or titration, is a method of quantitative chemical analysis to determine the unknown concentration of an analyte. There are three types of titrimetry: volumetric, gavimetric and coulometric.

3- Electroanalytical methods

Electroanalytical methods are a class of techniques in analytical chemistry which study an analyte by measuring the potential and/or current in an electrochemical cell containing the analyte. These methods are divided into several categories depending on which aspects of the cell are controlled and which are measured. The three main categories are potentiometry (the difference in electrode potentials is measured), coulometry (the cell's current is measured over time), and voltammetry (the cell's current is measured while altering the cell's potential).

4- Spectroscopy Molecular&Atomic

Spectroscopy is the study of the interaction between matter (atoms, molecules) and electromagnetic radiation. Spectroscopy can determine the structure and functional groups in compounds by different techniques such as Infrared or Raman spectroscopy which will be discussed.

5- Separation methods (GC, HPLC, IC)

Separation methods are used to separate, identify, and quantify each component in a mixture. Some of these techniques are: Gas chromatography (GC, High-performance liquid chromatography (HPLC), and Ion chromatography (IC).

Bibliography

Basic bibliography

- Fundamentals of Analytical Chemistry, by Skoog, West, Holler. Saunders College Publishing, Latest Edition.

- Principle of Instrumental Analysis, by D. A. Skoog, F. J. Holler, S. R. Crouch, Harcourt College

(1997).

- Analytical Separation Science, by Jared Anderson. Wiley-VCH 2016. DOI: 10.1002/9783527678129.

- Electroanalytical Methods: Guide to Experiments and Applications, by Fritz Scholz. Springer (2010).

- Atomic and Molecular Spectroscopy: Basic Aspects and Practical Applications, by Sune Svanberg. Springer (2004).