nireEHU 
Subject
Macromolecular Structure
General details of the subject
- Mode
- Face-to-face degree course
- Language
- English
Teaching staff
| Name | Institution | Category | Doctor | Teaching profile | Area | |
|---|---|---|---|---|---|---|
| FULLAONDO ELORDUI-ZAPATERIECHE, ASIER | University of the Basque Country | Profesorado Agregado | Doctor | Bilingual | Genetics | asier.fullaondo@ehu.eus |
| MORO PEREZ, FERNANDO | University of the Basque Country | Personal Doctor Investigador | Doctor | Not bilingual | Biochemistry and Molecular Biology | fernando.moro@ehu.eus |
Competencies
| Name | Weight |
|---|---|
| Conocimiento actualizado de las áreas más activas de la Biología Molecular y la Biomedicina. | 20.0 % |
| Experiencia de trabajo en un laboratorio de investigación en el área. | 20.0 % |
| Capacidad para comenzar el trabajo experimental conducente al doctorado. | 20.0 % |
| Capacidad para comprender y, a nivel básico, evaluar críticamente un artículo de investigación en las áreas objeto del Máster. | 20.0 % |
| Capacidad para iniciar una tesis doctoral. | 20.0 % |
Study types
| Type | Face-to-face hours | Non face-to-face hours | Total hours |
|---|---|---|---|
| Lecture-based | 50 | 75 | 125 |
Training activities
| Name | Hours | Percentage of classroom teaching |
|---|---|---|
| Acquiring basic instrumental skills | 25.0 | 8 % |
| Expositive classes | 50.0 | 24 % |
| Text analysis | 50.0 | 8 % |
Assessment systems
| Name | Minimum weighting | Maximum weighting |
|---|---|---|
| Continuous evaluation | 0.0 % | 30.0 % |
| Multiple-choice examination | 0.0 % | 30.0 % |
| OTROS | 0.0 % | 10.0 % |
| Oral examination | 0.0 % | 30.0 % |
Learning outcomes of the subject
Comprensión de las técnicas experimentatles usadas en la determinación de la estructura tridimensional demacromoléculas biológicas
Ordinary call: orientations and renunciation
Attendance is compulsory, and attendance of 80% or more is required to pass the course. Attendance and participation, questions, discussion of articles, 70% of the evaluation, oral exam (powerpoint presentation) 30%.This method of assessment could be changed if the guidelines of the health authorities so provide. The appropriate modifications would be announced in due course, with the necessary strategies and tools to guarantee the right of the student to be evaluated with equity and fairness.
Extraordinary call: orientations and renunciation
Taking a written test of the entire syllabus.This method of assessment could be changed if the guidelines of the health authorities so provide. The appropriate modifications would be announced in due course, with the necessary strategies and tools to guarantee the right of the student to be evaluated with equity and fairness.
Temary
Tema 1 INTRODUCCIÓN A LA ESTRUCTURA DE PROTEÍNASTema 2 ESTRUCTURA SECUNDARIA DE PROTEÍNAS
Tema 3 TÉCNICAS ESPECTROSCÓPICAS PARA ESTIMAR LA ESTRUCTURA SECUNDARIA DE PROTEÍNAS Y DETERMINAR MECANISMOS DE REACCIÓN
Tema 4 ESTRUCTURA TERCIARIA Y CUATERNARIA DE PROTEÍNAS
Tema 5 PROTEÍNAS DE MEMBRANA
Tema 6 DETERMINACIÓN DE LA ESTRUCTURA TERCIARIA DE PROTEÍNAS I: CRISTALOGRAFÍA Y DIFRACCIÓN DE RAYOS X
Tema 7 DETERMINACIÓN DE LA ESTRUCTURA TERCIARIA DE PROTEÍNAS II: MICROSCOPÍA ELECTRÓNICA
Tema 8 ESTABILIDAD TERMODINÁMICA DE PROTEÍNAS
Tema 9 PLEGAMIENTO DE PROTEÍNAS EN LA CÉLULA
Tema 10 PLEGAMIENTO DEFECTUOSO Y ENFERMEDADES
Tema 11 PREDICCION ESTRUCTURA DE PROTEINAS
Tema 12 MOTORES MOLECULARES
Tema 13 NANOBIOTECNOLOGÍA
Tema 14 ESTRUCTURA Y TOPOLOGÍAS DEL DNA
Tema 15 ESTRUCTURA SECUNDARIA Y TERCIARIA DE RNAS
Tema 16 RECONOCIMIENTO MACROMOLECULA-LIGANDO
Tema 17 INTERACCIONES MACROMOLECULARES
Tema 18 EVOLUCION MOLECULAR DE PROTEINAS
Tema 19 INGENIERIA DE PROTEINAS
Bibliography
Compulsory materials
For each individual subject included in the program the student will be provided by the instructors with additional teaching aids (i.e Power Point presentations and other specialized references as reviews or research articles)in the digital platform Moodle.Basic bibliography
1) Gómez-Moreno, C y Sancho, J (coordinadores) "ESTRUCTURA DE PROTEÍNAS". Ed. Ariel 20032) Creigthon, T. "PROTEINS. STRUCTURE AND MOLECULAR PROPERTIES" 2ª ed. Freeman. 1993
3) Branden, Tooze. "INTRODUCTION TO PROTEIN STRUCTURE" 2ª ed. Garland 1999
4) LESK, A. "AN INTRODUCTION TO PROTEIN ARCHITECTURE: THE STRUCTURAL BIOLOGY OF PROTEINS." OXFORD UNIVERSITY PRESS, 2001
5) Kyte "STRUCTURE IN PROTEIN CHEMISTRY", Garland 1995
6) Darby, Creigthon "PROTEIN STRUCTURE" IRL Press. Oxford University Press 1993
7) Rhodes, G "CRYSTALLOGRAPHY MADE CRYSTAL CLEAR". 2ª ed. Academic Press 2000
8) Sinden, "DNA STRUCTURE AND FUNCTION". Academic Press, 1994.
9) Blomfield, Crothers, Tinoco, "NUCLEIC ACIDS: STRUCTURE, PROPERTIES AND FUNCTION". University Science Books, 2000