Learning outcomes of the subject

Capacidad de desarrollo de una actividad científica

Ordinary call: orientations and renunciation

Attendance is compulsory, attendance of 80% or more is required to pass the course

The evaluation will be done continuously in the classroom by means of that test that the teaching staff considers appropriate in each session (e.g. multiple choice test, development questions, oral evaluation, etc.). In each session a continuous evaluation will be made by the teaching staff. The sum of the grades of the different evaluations of the teaching staff will correspond to the final grade of this part of the course. Grade 0-10 points. (50% evaluation)

The 'Work' will be written and chosen by the students from among the topics proposed by the teachers. Grade 0-10 points. (50% evaluation)

The FINAL RATING will be obtained from the average mark of the Evaluation and Work sections.





This method of assessment could be changed if the guidelines of the health authorities so provide. The appropriate modifications would be announced in due course, with the necessary strategies and tools to guarantee the right of the student to be evaluated with equity and fairness.





This method of assessment could be changed if the guidelines of the health authorities so provide. The appropriate modifications would be announced in due course, with the necessary strategies and tools to guarantee the right of the student to be evaluated with equity and fairness.

Extraordinary call: orientations and renunciation

Taking a written test of the entire syllabus.

This method of assessment could be changed if the guidelines of the health authorities so provide. The appropriate modifications would be announced in due course, with the necessary strategies and tools to guarantee the right of the student to be evaluated with equity and fairness.

Temary

Item 1 FUNDAMENTALS OF THE ORGANIZATION OF THE EUKARYOTIC CELL

Item 2 CELLULAR BASES OF TRANSCRIPTION

Item 3 CELLULAR BASES OF NUCLEAR pre-mRNA PROCESSING

Item 4 CELLULAR BASES OF SYNTHESIS AND RNA PROCESSING: NUCLEOLUS

Item 5 CELLULAR BASES OF THE UBIQUITINE-PROTEASOME NETWORK ORGANIZATION

Item 6 NORMAL CELLS VS TUMOR CELLS

Item 7 HEMATOENCEPHALIC BARRIER CELL BIOLOGY (BHE)

Item 8 CELL BIOLOGY OF BLOOD-BARRIER CEFALORRACHIDES (CSF)

Item 9 INTRACEREBRAL CELL AND TISSUE TRANSPLANTS: APPLICATION TO THE STUDY OF ANGIOGENESIS AND THE HEMATOENCHEPHALIC BARRIER (BHE)

Item 10 "IN VITRO" AGING

Item 11 "LIVE" AGEING

Item 12 AGEING BIOMARKERS

Item 13 INTRODUCTION TO EMBRIONARY DEVELOPMENT MODELS OF EMBRYONIC DEVELOPMENT. EARLY STAGES OF EMBRYONIC DEVELOPMENT

Item 14 SPECIFICATION OF PRIMARY EMBRYOUS AXES

Item 15 REGULATION OF GENIC EXPRESSION DURING DEVELOPMENT

Item 16 DIFFERENTIATION AND MATURATION OF THE NEURONAL LINEAGE

Item 17 NEURODEGENERATION AT THE CELLULAR LEVEL

Item 18 EMBRYOUS MODELS IN THE STUDY OF CELL MIGRATION

Item 19 EPITELIUM-MESENCHEME TRANSITION DURING DEVELOPMENT

Item 20 POLARIZATION AND ADHESION IN CELL MIGRATION DURING EMBRYONARY MORPHOGENESIS

Item 21 EMBRIONARY DEVELOPMENT OF BLOOD CELLS AND THE IMMUNITY SYSTEM

Item 22 EMBRYOUS DEVELOPMENT OF BLOOD VESSELS

Item 23 REGULATION AND ROLE OF CELL DEATH DURING EMBRIONARY DEVELOPMENT I

Item 24 REGULATION AND ROLE OF CELL DEATH DURING EMBRIONARY DEVELOPMENT II

Bibliography

Compulsory materials

For each individual subject included in the program the student will be provided by the instructors with additional teaching aids (i.e Power Point presentations and other specialized references as reviews or research articles).

Basic bibliography

1.- Cell biology. Thomas D. Pollard y william C. Earnshaw. Saunders

2.- Cell and Molecular Biology. Concepts and Experiments. Gerald Karp 3RD Ed. John Wiley and Sons,INC 3.- Physiological Basis of Aging and Geriatrics. Editado por P.S.Timiras CRC Press 2003

4.- Biogerontología. Editado por D.Crespo. Universidad de Cantabria 2006.

5.- Neuroscience. 2nd ed. Purves, Dale; Augustine, George.J.; Fitzpatrick, David; Katz, Lawrence.C.; LaMantia, Anthony-Samuel.;McNamara, James.O.; Williams, S. Mark, editors.Sunderland (MA): Sinauer Associates, Inc. c2001.(http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=neurosci)

6.-Basic Neurochemistry, Molecular, Cellular, and Medical Aspects 6th ed.

Siegal, George J.; Agranoff, Bernard W.; Albers, R. Wayne; Fisher, Stephen K.; Uhler, Michael D., editors.Philadelphia: Lippincott, Williams & Wilkins; c1999. (http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=bnchm)

7.- Developmental Biology. Eighth Edition. By Scott F. Gilbert Sinauer Aaasociated Eds

8.- Principles of development Lewis Wolpert, Rosa Beddington, Thomas Jessell, Peter Lawrence, Elliot Meyerowitz and Jim Smith. 2nd Ed. Oxford university press

In-depth bibliography

1.- Cell biology. Thomas D. Pollard y william C. Earnshaw. Saunders



2.- Cell and Molecular Biology. Concepts and Experiments. Gerald Karp 3RD Ed. John Wiley and Sons,INC



3.- Physiological Basis of Aging and Geriatrics. Editado por P.S.Timiras CRC Press 2003



4.- Biogerontología. Editado por D.Crespo. Universidad de Cantabria 2006.



5.- Neuroscience. 2nd ed. Purves, Dale; Augustine, George.J.; Fitzpatrick, David; Katz, Lawrence.C.; LaMantia, Anthony-Samuel.;McNamara, James.O.; Williams, S. Mark, editors.Sunderland (MA): Sinauer Associates, Inc. c2001.(http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=neurosci)



6.-Basic Neurochemistry, Molecular, Cellular, and Medical Aspects 6th ed.



Siegal, George J.; Agranoff, Bernard W.; Albers, R. Wayne; Fisher, Stephen K.; Uhler, Michael D., editors.Philadelphia: Lippincott, Williams & Wilkins; c1999. (http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=bnchm)



7.- Developmental Biology. Eighth Edition. By Scott F. Gilbert Sinauer Aaasociated Eds



8.- Principles of development Lewis Wolpert, Rosa Beddington, Thomas Jessell, Peter Lawrence, Elliot Meyerowitz and Jim Smith. 2nd Ed. Oxford university press

Links

Human Ageing Genomic Resources.http://genomics.senescence.info/ National institute of Aging.



American Society on Aging. http://www.asaging.org/index.cfm