Congratulations Maite! A new paper from your thesis work has just been accepted for publication in Biosensors & Bioelectronics.

The paper entitled: An Electroactive and Thermo-responsive Material for the Capture and Release of Cells by M. Garcia-Hernando, J. Saez, A. Savva, L. Basabe-Desmonts, R. M. Owens, and F. Benito-Lopez is a collaboration with University of Cambridge.

Biosens. Bioelectron.: IF: 10.257.

Abstract

Non-invasive collection of target cells is crucial for research in biology and medicine. In this work, we combine a thermo-responsive material, poly(N-isopropylacrylamide), with an electroactive material, poly(3,4-ethylene-dioxythiopene):poly(styrene sulfonate), to generate a smart and conductive copolymer for the label-free and non-invasive detection of the capture and release of cells on gold electrodes by electrochemical impedance spectroscopy. The copolymer is functionalized with fibronectin to capture tumor cells, and undergoes a conformational change in response to temperature, causing the release of cells. Simultaneously, the copolymer acts as a sensor, monitoring the capture and release of cancer cells by electrochemical impedance spectroscopy. It is expected that this platform has the potential to play a role in top-notch label-free electrical monitoring of human cells obtaining in clinic.

GREAT JOB TEAM!