GENERAL SKILLS:

1.Ability to gather and interpret relevant data to evaluate risk/benefit ratio of the diagnostic and therapeutic procedures.

2.Knowledge of the indications of immunological and microbiological tests.

3.Knowledge of biochemical and molecular biology markers and its use to clinical diagnosis.

4.Learn the fundamentals of Microbiology and Immunology, the major human infectious agents and their mechanisms of action.

5.Learn the main techniques of microbiological and immunological diagnosis and interpretation of results.

6.Knowledge about the mechanisms of action of antimicrobial agents

7.Learn how to obtain and process a biological sample for study using the different diagnostic procedures.

8.Knowledge about sterilization and disinfection techniques.



Transversal Skills:

-Develop skills for working in teams with respect to profesionals belonging to different health areas.

-Risk assessment. Developing the ability to identify and understand the risks associated with multi-step integrated process.

-Critical reasoning and reading. Build knowledge about key types and sources of scientific information and articles, as well as developing the skills to be able to critically evaluate their usefulness and worth.

- Learn about the application of biological research in the health sciences.

-Problem solving. Be able to discuss and critically develop protocols and strategies for solving complex problems using an array of sources of information.

- Oral presentation. Develop skills in oral presentation of highly detailed material to a variety of audiences.

-Gender, health and sustainable development.



SPECIFIC SKILLS:

1.Knowledge of the scientific fundamentals of Medical Microbiology and Parasitology

2.Understand the mechanisms of microbial pathogenicity and the antimicrobial immune response.

3.Knowledge of how to obtain and manage in the laboratory the most appropriate clinical sample to the most prevalent infectious diseases.

4.Evaluate the need of diagnostic and therapeutic procedures.interpretation of results and making decisions about antimicrobial therapy.

MODULE I: INTRODUCTION 3Lectures + Computer-based SessionCbS1( glossary, basic terminology)

. The microbial world.

. Microorganisms and human beings.

. Characteristics of the host-parasite interactions



MODULE II: DIAGNOSTICS, TREATMENT AND CONTROL 3Lectures+ 1 Classroom Practical Sessions CPS1 vaccines, CPS2 antibiotics y CPS 4 diagnosis of viruses + CbS2 infection control

. Laboratory diagnosis of infectious diseases

. Control of microorganisms: microbiological basis of antimicrobial therapies.

. Sterilization and Disinfection

. Epidemiology and prophylaxis of infectious diseases.



MODULE III: IMMUNE DEFENSES AGAINST MICROBES 10Lectures + Students work(Seminar 1, CPS 3 Microbial Pathogenicity and CbS3,CbS4,CbS5,S2, CbS6)

. General features and early defense against infection (2 hours)

. Innate Immunity (2 hours)

. Adaptive Immunity

. Antigen capture and presentation to T Lymphocytes.

. Activation of T & BLymphocytes (2 hours)

. Effector mechanisms in the adaptive immune system

. Immunopathology



MODULE IV: PATHOGENIC BACTERIA 9 Lectures +Student’s work(S1, CPS3 CbS3,CbS4,CbS5,S2,CPS6)

. General characteristics of pathogenic bacteria (2 hours)

. Gram-positive Cocci.

. Gram-positive Rods

. Gram-negative Cocci.

. Gram-negative Rods (2 hours)

. Mycobacteria.

. Anaerobes.

. Other pathogenic bacteria. Spirochaetaceae, Rickettsiaceae, Chlamydiaceae andMycoplasmataceae



MODULE V: PATHOGENIC VIRUSES. 9L + CPS5 introduction to pathogenic viruses +Student’s work (S1, CPS3 and CbS3,CbS4,CbS5,S2,CPS6)

. General characteristics of viruses and human prions (CPS5)

. DNAviruses. Herpesviruses (2 hours)

. DNAviruses. Papillomaviruses and Parvoviruses.

. RNA viruses. Viruses causing respiratory tract infections

. RNA viruses. Enteroviruses and viruses causing exanthems.

. Hepatitis viruses.

. Retroviruses (2 hours)



MODULE VI: PATHOGENIC PROTOZOA, HELMINTS AND FUNGI. 3Lectures + Student’s work (S1, CPS3 and CbS3,CbS4,CbS5,S2,CPS6)

. Medically important protozoa

. Medically important helminths

. Medically important fungi



MODULE VII: LABORATORY DIAGNOSIS 9 LP + CbS6 Laboratory Diagnosis

Sterilization and disinfection techniques

Specimen management and cultures

Identification of pathogenic bacteria

Antimicrobial susceptibility

Identification of fungi: molds and yeasts

Identification of protozoa and helminths

Antigen detection (agglutination) and bacterial genome analysis

Indirect diagnostic methods: ELISA





Seminars:

Student’s work: the students will prepare information about pathogenicity, immune response and mechanisms of transmission of a given microorganism. Cada alumno/a resumirá los principales datos obtenidos en una ficha.

S1: Presentation

S2: Oral Exposition



Computer-based Sessions:

CbS1: Information

CbS2: Control of Infection

CbS3: Student’s work

CbS4: Student’s work

CbS5: Student’s work. Exercises.

CbS6. Microbiological diagnosis. Clinical cases



Classroom Practical Sessions:

CPS1: Antibiotics and resistance

CPS2: Pathogenicity. Exercises, evaluation,

CPS3: Vaccines

CPS4: Diagnosisofviruses. Exercises

CPS5: Introduction to viruses.Exercises

CPS6: Evaluation, student’s work



Laboratory Sessions:

LS1. ELISA

LS2. AGGLUTINATION AND ANALYSIS OF BACTERIAL DNA

LS3. STAINS

LS4. PARASITES AND FUNGI(A)

LS5.FUNGI(B)

LS6. PATHOGENIC BACTERIA 1. Specimen management and cultures

LS7.PATHOGENICBACTERIA 2. Phenotypic identification

LS8. PATHOGENIC BACTERIA 3. Interpretation of results

LS9. EXAM

36 hours for master classes + 3 hours for evaluations

1.- Theoretical Examination

-A: Theory test, 60 questions (0.3 negative punctuation for wrong answers).

-B: Evaluation of course content by problem-based exercise, tables, etc. (Distinction task)

-60% : A (test passed)

-10%: B



Assessment details:60 multiple choice questions with four options, only one is correct. Value of correct answer is 1 positive point, wrong answer 0.3 negative points.There is no penalization for questions not answered. In the theory examination there will be a 15% of the content belonging to classroom practical and computer-based sessions. To pass the exam students must obtain at least a 50% of the total score. Summative of the corresponding 40% only will be taken in account when test A is passed. Wrong answers in test B will not have negative value.



2.- Laboratory examination

- 15 (negative punctuation for wrong answers) -15% (exam passed is mandatory)



Assessment details:exam will be a final test consisting onpractical questions based on images or real laboratory testswith a global punctuation 15. One positive for each correct answer and one negative for wrong ones. No penalization for questions not answered..To pass the exam you must obtain at least a 50% of the total score. Active participation and attendance practical sessions is mandatory with a possibility of a 5% penalization for absence with no official justification.Mark will only be taken in account when passed.

Repeating students don’t need to attend practical sessions but they must pass the exam.



3.- Continuousassessment and independent work

- Independent student’s work about a pathogen 15%



Assessment details: Active participation, oral presentations and individual work. Attendance to sessions is mandatory (it could be penalty of 5% of the mark for practical sessions and/or 10% of individual work)

The use of lab coat is mandatory in the laboratory classes

Basic bibliography

1-Medical Microbiology8thEd. 2017 .Patrick Murray, Ken S. Rosenthal, Michael A. Pfaller. Elsevier.



2-Basic Immunology6th Ed. 2017. Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai. Elsevier

In-depth bibliography

1-Mims’ Medical Microbiology. 6th Ed. 2018.Richard V Goering, Hazel M Dockrell, Mark Zuckerman, Derek Wakelin, Ivan M Roitt, Cedric Mims, Peter L. Chiodini.Elsevier

2-Cellular and Molecular Immunology. 9th Ed.2017. Abul K. Abbas, Andrew H.Lichtman, .Elsevier.

Journals

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