Argitalpenak

Conjugate Addition of Amines to an α,β-Unsaturated Imine Derived from α-Aminophosphonate. Synthesis of γ-Amino-α-dehydroaminophosphonates

Egileak:
Javier Vicario, Domitila Aparicio, Francisco Palacios
Urtea:
2009
Aldizkaria:
The Journal of Organic Chemistry
Liburukia:
74
Hasierako orria - Amaierako orria:
452 - 455
Deskribapena:

Aza-Michael reaction of ammonia, aliphatic, aromatic and optically active amines to an α,β-unsaturated imine derived from α-aminophosphonate affords α-dehydroaminophosphonates with a γ-stereogenic center bearing an amino group. Resulting γ-amino α-dehydroaminophosphonates can be used for the preparation of phosphorylated pyrimidine derivatives.

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