GENERAL RADIOISOTOPE SERVICE

Different scientific disciplines regularly develop a great variety of experiments with the absolute requirement of radioactive isotopes. Different departments at the Faculty of Science and Technology are currently using the Service within the following contexts:

• Monitoring of metabolytes marked in the different metabolic routes of animals, plants and microorganisms.
• Study into the cell cycle and behaviour of cyclines.
• Studies into the regulation of syntheses and degradation of nucleic acids and the study of gene expression using PCR techniques (Polymerase Chain Reaction).
• Regulation of cell activation by proto-oncogenes and cytokines.
• Control of cell proliferation and death (apoptosis/necrosis).
• Determination of intracellular second messengers and the study of the different routes of cellular signalling.
• Study and characterization of membrane receptors with radioligands.
• Detection and determination of biological molecules via commercial kits that contain radioactive isotopes.
• Analysis of cyclic nucleotides by radioimmunotest (RIA).
• Measurements of enzymatic activities.