Europe has a solid research and industrial base and is the home of bold, creative entrepreneurs. Yet it often needs to strengthen the use of its scientific excellence and industrial prowess to accelerate innovation and turn innovative SMEs into global technology giants. By reinforcing close cross-border collaboration between multiple actors, including academia, the public sector, industry and individual entrepreneurs, Horizon Europe aims to develop radical solutions to pressing societal challenges and fostering sustainable economic growth and employment. Through its Pillar III ‘Innovative Europe’, the programme will focus on supporting the development of disruptive and market-creating innovations and on enhancing European innovation ecosystems.