Publications 2025

Iragorri, N.; Hurtado, J.; Vicario, J. L.; Reyes, E.; Fernandez, E. "Preparation of Enantioenriched Spirocyclic Scaffolds Transferring Axial Chirality from Borylalkylidenecycloalkanes" ChemistryEurope 2025, 3, e202500185.
Campos, J.; Uria, U. "La Química en México: Desafíos y Oportunidades" An. Quim. 2025, 121, 123-126.
Garcia, L.; Carrillo, L.; Reyes, E.; Uria, U.; Prieto, L. "Organocatalytic Enantioselective Nitro-Vinylcyclopropane-Cyclopentene Rearrangement; Expanding the Reactivity of Donor-Acceptor Cyclopropanes" Synthesis 2025, 57, 3350-3360.
Campos, J.; Uria, U. "La Inteligencia artificial en la investigación química" An. Quim. 2025, 121, 6-10.
Avellanal-Zabale, E.; Prieto, L.; Casado, N.; Uria, U.; Reyes, E.; Bañuelos, J. "Benzo[f]indazoles: A new class of glow dyes for the generation of versatile fluorophores" Dyes and Pigments 2025, 235, 112624.

Publicaciones 2024

Publications 2024

Hurtado, J.; Iragorri, N.; Reyes, E.; Fernandez, E.; Vicario, J. L. "Cu-Catalyzed Enantioselective Borylative Desymmetrization of 1-Vinyl Cyclobutanols and Axial-to-Point Chirality Transfer in a Diastereoconvergent/Stereoretentive Allylation Scenery" Angew. Chem. Int. Ed. 2024, 63, e202411232.
Reyes, E.; Uria, U.; Prieto, L.; Carrillo, L.; Vicario, J. L. "Organocatalysis as an enabling tool for enantioselective ring-opening reactions of cyclopropanes" Chem. Commun. 2024, 60, 7288-7298.
Pedron, M. Villar, L.; Uria, U.; Prieto, L.; Tejero, T.; Merino, P.; Vicario, J. L. "Mechanistic Insights on the Enantioselective (4+3) Cycloaddition Between Oxyallylcations and Furans Catalyzed by BINOL-Based Phosphoramides" Adv. Synth. Catal. 2023, 366, 916-924.

Publicaciones 2023

Publications 2023

Pedron, M.; Sendra, J.; Gines, I.; Tejero, T.; Vicario, J. L.; Merino, P. "Computational studies of Brønsted acid-catalyzed transannular cycloadditions of cycloalkenone hydrazones" Beilstein J. Org. Chem. 2023, 19, 477–486.
Wang, Y.; Goikolea, E.; Ruiz de Larramendi, I.; Reyes, E.; Lanceros-Mendez, S.; Zhang, Q. "Natural and recyclable alginate hydrogels as extracting media for recovering valuable metals of spent lithium-ion batteries from a deep eutectic solvent" Waste Management 2023, 171, 271-280.
Homölle, S. L.; Stangier, M.; Reyes, E.; Ackermann, L. "Bifurcated Rhodaelectro-Catalyzed C–H Activation for the Synthesis of Pyrroles and Lactones" Precision Chem. 2023, 1, 382-387.
Prieto, L.; Reyes, E.; Uria, U.; Carrillo, L.; Vicario, J. L. "Desymmetrization of Oxabenzonorbornadienes through Brønsted Acid Catalyzed Enantioselective (3+2) Cycloaddition with Hydrazones" Asian J. Org. Chem. 2023, 12, e202300163.
Reyes, E.; Prieto, L.; Uria, U.; Carrillo, L.; Vicario, J. L. "Asymmetric dual enamine catalysis / hydrogen bonding activation" Catalysts 2023, 13, 1091.
Reyes, E.; Uria, U.; Prieto, L.; Carrillo, L.; Vicario, J. L. "Organocatalytic activation of cyclopropanes in asymmetric synthesis" Tetrahedron Chem. 2023, 7, 100041.
Prieto, L.; Reyes, E.; Uria, U.; Carrillo, L.; Vicario, J. L. "2021. Kimikako Nobel Saria natura imitatzeari. Biomimetikaren eragina organokatalisiaren garapenean" Ekaia, 2023, 43, 59-66.
Garay, G.; Hurtado, J.; Pedron, M.; Garcia, L.; Reyes, E.; Sanchez-Diez, E.; Tejero, T.; Merino, P.; Vicario, J. L. "Catalytic Enantioselective Vinylcyclopropane-Cyclopentene (VCP-CP) Rearrangement" Angew. Chem. Int. Ed. 2023, 62, e202302416.
Sendra, J.; Salvado, O.; Pedron, M.; Reyes, E.; Tejero, T.; Fernandez, E.; Merino, P.; Jose L. Vicario. "Switchable Brønsted acid-catalyzed ring contraction of cyclooctatetraene oxide towards the enantioselective synthesis of cycloheptatrienyl-substituted homoallylic alcohols and oxaborinanes" Adv. Synth. Catal. 2023, 365, 1058-1071.
Reyes, E.; Prieto, L.; Milelli, A. "Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists" Molecules 2023, 28, 271.

Publicaciones 2022

Publications 2022

Reyes, E.; Prieto, L.; Uria, U.; Carrillo, L.; Vicario, J. L. "Recent Advances in the Prins Reaction" ACS Omega 2022, 7, 31621-31627.
Luis-Barrera, J.; Rodriguez, S.; Uria, U.; Reyes, E.; Prieto, L.; Carrillo, L.; Pedron, M.; Tejero, T.; Merino, P.; Vicario, J. L. "Brønsted acid vs phase-transfer catalysis in the enantioselective transannular aminohalogenation of enesultams" Chem. Eur. J. 2022, e202202267.
Capel, E.; Luis-Barrera, J.; Sorazu, A.; Uria, U.; Prieto, L. Reyes, E.; Carrillo, L.; Vicario, J. L. "Transannular Approach to 2,3-Dihydropyrrolo[1,2-b]isoquinolin-5(1H)-ones through Brønsted Acid-Catalyzed Amidohalogenation" J. Org. Chem. 2022, 87, 10062-10072.
Prieto, L.; Rodriguez, V.; Vicario, J. L.; Reyes, E.; Hornillos, V. "Enantioselective Transannular Reactions by Palladium-Catalysed Conjugate Addition of Aryl Boronic Acids" Chem. Commun. 2022, 58, 6514-6517.
Reyes, E.; Prieto, L.; Carrillo, L.; Uria, U.; Vicario, J. L. "Recent Developments in Transannular Reactions" Synthesis 2022, 54, 4167-4183.
Maldonado, N.; Beobide, G.; Reyes, E.; Martinez, J. I.; Gomez-Garcia, C. J.; Castillo, O.; Amo-Ochoa, P. "Innovative Microstructural Transformation upon CO2 Supercritical Conditions on Metal-Nucleobase Aerogel and Its Use as Effective Filler for HPLC Biomolecules Separation" Nanomaterials 2022, 12, 675.

Capel, E.; Rodriguez-Rodriguez, M.; Uria, U.; Pedron, M.; Tejero, T.; Vicario, J. L.; Merino, P. "Absence of Intermediates in the BINOL-Derived Mg(II)/Phosphate-Catalyzed Desymmetrizative Ring Expansion of 1-Vinylcyclobutanols" J. Org. Chem. 2022, 87, 693-707.
Mato, R.; Manzano, R.; Reyes, E.; Prieto, L.; Uria, U.; Carrillo, L.; Vicario, J. L. "Kinetic Resolution in Transannular Morita-Baylis-Hillman Reaction: An Aproximation to the Synthesis of Sesquiterpenes from Guaiane Family" Catalysts 2022, 12, 67.
Ugarriza, I.; Reyes, E.; Prieto, L.; Uria, U.; Carrillo, L.; Vicario, J. L. "An Approach to the Synthesis of a Hepatitis C Virus Inhibitor through a Proline-Catalyzed 1,3-Dipolar Cycloaddition Using Acrolein" Synthesis 2021, 54, 1101-1107.

Publicaciones 2021

Publications 2021

Masson-Makdissi, J.; Prieto, L.; Abel-Snape, X.; Lautens, M. "Enantio- and Diastereodivergent Sequential Catalysis Featuring Two Transition-Metal-Catalyzed Asymmetric Reactions" Angew. Chem. Int. Ed. 2021, 60, 16932-16936.
Sendra, J.; Reyes, E.; Prieto, L.; Fernandez, E.; Vicario, J. L. "Transannular Enantioselective (3 + 2) Cycloaddition of Cycloalkenone Hydrazones under Brønsted Acid Catalysis" Org. Lett. 2021, 23, 8738-8743.
Rodriguez, S.; Uria, U.; Reyes, E.; Prieto, L.; Rodriguez-Rodriguez, M.; Tejero, T.; Merino, P.; Vicario, J. L. "The pseudotransannular ring opening of 1‐aminocyclohept‐4‐ene‐derived epoxides in the synthesis of tropane alkaloids. Total synthesis of (±)‐Ferrugine" Eur. J. Org. Chem. 2021, 20, 2855-2861.
Ortega, A.; Uria, U.; Tejero, T.; Prieto, L.; Reyes, E.; Merino, P.; Vicario, J. L. "Brønsted Acid-Catalyzed (4+2) Cyclocondensation of 3-Substituted Indoles with Donor-Acceptor Cyclopropanes" Org. Lett. 2021, 23, 2326-2331.
Rodriguez, S.; Uria, U.; Reyes, E.; Prieto, L.; Rodriguez-Rodriguez, M.; Carrillo, L.; Manzano, R.; Vicario, J. L. "Enantioselective construction of the 8-azabicyclo[3.2.1]octane scaffold: application in the synthesis of tropane alkaloids" Org. Biomol. Chem. 2021, 19, 3763-3775.

Publicaciones 2020

Publications 2020

Mato, R.; Reyes, E.; Carrillo, L.; Uria, U.; Prieto, L.; Manzano, R.; Vicario, J. L. "Catalytic enantioselective domino Michael/transannular aldol reaction under bifunctional catalysis" Chem. Commun. 2020, 56, 13149-13152.
Manzano, R.; Romaniega, A.; Prieto, L.; Diaz, E.; Reyes, E.; Uria, U.; Carrillo, L.; Vicario, J. L. "γ-Substituted allenic amides in the phosphine-catalyzed enantioselective higher order cycloaddition with azaheptafulvenes" Org. Lett. 2020, 22, 4721–4725.
Vegas, V. G.; Beobide, G.; Castillo, O.; Reyes, E.; Gomez-Garcia, C. J.; Zamora, F.; Amo-Ochoa, P. "Bioinspired Metal-Organic approach to cross-linked functional 3D nanofibrous Hydro and Aero-gels with Effective Mixtures Separation of Nucleobases by Molecular Recognition" Nanoscale, 2020, 12, 14699-14707.
White, A.; Torelli, A.; Mirabi, B.; Prieto, L.; Rodriguez, J.; Lautens, M. "Cobalt-Catalyzed Enantioselective Hydroarylation of 1,6-Enynes" J. Am. Chem. Soc. 2020, 142, 9510-9517.
Rodriguez, S.; Uria, U.; Reyes, E.; Carrillo, L.; Tejero, T.; Merino, P.; Vicario, J. L. "Enantioselective Synthesis of Tropanes through Brønsted Acid‐Catalyzed Pseudotransannular Desymmetrization" Angew. Chem. Int. Ed. 2020, 59, 6780-6784.
Sendra, J.; Manzano, R.; Reyes, E.; Vicario, J. L.; Fernández, E. "Catalytic Stereoselective Borylative Transannular Reactions" Angew. Chem. Int. Ed. 2020, 59, 2100-2104.

Publicaciones 2019

Publications 2019

Masson-Makdissi, J.; Jang, Y. J.; Prieto, L.; Taylor, M. S.; Lautens, M. "Rhodium-Catalyzed Tandem Isomerization–Allylation: From Diallyl Carbonates to α-Quaternary Aldehydes" ACS Catal. 2019, 9, 11808-11812.
Whyte, A.; Mirabi, B.; Torelli, A.; Prieto, L.; Bajohr, J.; Lautens, M. "Asymmetric Synthesis of Boryl-Functionalized Cyclobutanols" ACS Catal. 2019, 9, 9253-9258
Mato, R.; Manzano, R.; Reyes, E.; Carrillo, L.; Uria, U.; Vicario, J. L "Catalytic Enantioselective Transannular Morita−Baylis−Hillman Reaction" J. Am. Chem. Soc. 2019, 141, 9495-9499.
Reyes, E. "Z=97 Berkelio - el primero de una larga serie" An. Quim. 2019, 115, 159.
Manzano, R. "Z=98 Californio - el elemento más pesado con aplicaciones" An. Quim. 2019, 115, 160.
Reyes, E. "Reacción de hidroboración de olefinas: 60 años desde su descubrimiento y 40 años desde la concesión del premio Nobel a Herbert C. Brown" An. Quim. 2019, 115, 300-307.

Publicaciones 2018

Publications 2018

Villar, L.; Orlov, N. K.; Kondratyev, N. S.; Uria, U.; Vicario, J. L.; Malkov, A. I. "Kinetic Resolution of Secondary Allyl Boronates and Their Application in the Synthesis of Homoallylic Amines" Chem. Eur. J. 2018, 24, 16262-16265.
Zabaleta, N.; Uria, U.; Reyes, E.; Carrillo, L.; Vicario, J. L. "Ion-Pairing Catalysis in the enantioselective Addition of Hydrazones to N-Acyldihydropyrrole Derivatives" Chem. Commun. 2018, 57, 8905-8908.
Garcia, L.; Sendra, J.; Miralles, N.; Reyes, E.; Carbo, J. J.; Vicario, J. L.; Fernandez, E. "Transition-metal-free stereoselective borylation of allenamides" Chem. Eur. J. 2018, 24, 14059-14063.
Ortega, A.; Manzano, R.; Uria, U.; Carrillo, L.; Reyes, E.; Tejero, T.; Merino, P.; Vicario, J. L. "Catalytic Enantioselective Cloke-Wilson Rearrangement" Angew. Chem. Int. Ed. 2018, 57, 8225-8229 (Highlighted in Synfacts, 2018, 868).
Diaz-Soto, E.; Reyes, E.; Uria, U.; Carrillo, L.; Tejero, T.; Merino, P.; Vicario, J. L. "Carboxylates as Nucleophiles in the Enantioselective Ring-Opening of Formylcyclopropanes under Iminium Ion Catalysis" Chem. Eur. J. 2018, 24, 8764-8768.
Riaño, I., Uria, U.; Reyes, E.; Carrillo, L.; Vicario, J. L. "Organocatalytic Transannular Approach to Stereodefined Bicyclo[3.1.0]hexanes" J. Org. Chem. 2018, 83, 4180-4189.
Reboredo, S.; Garcia-Marijuan, A.; Uria, U.; Reyes, E.; Carrillo, L.; Ugarriza, I.; Vicario, J. L. "Highly Diastereoselective C → N Acyl Rearrangement in Polysubstituted Pyrrolidine 2,2-Dicarboxylates. Stereocontrolled Synthesis of Densely Functionalized Prolines" Org. Chem. Front. 2018, 3, 933-942.
Reyes, E.; Uria, U.; Carrillo, L.; Vicario, J. L. "Reacciones organocatalíticas de cicloadición: desarrollo de estrategias eficaces en la síntesis enantioselectiva de carbo- y heterociclos complejos" An. Quim. 2018, 114, 231-240.

Publicaciones 2017

Publications 2017

Juste-Navarro, V.; Prieto, L.; Delso, I.; Manzano, R.; Tejero, T.; Reyes, E.; Vicario, J. L.; Merino, P. "A Case Study of Thiourea-Assisted Iminium Formation by Hydroxyl Anion Binding: Kinetic, Spectroscopic and Computational Evidences" Adv. Synth. Catal. 2017, 359, 4122-4128.
Sce, F.; Beobide, G.; Castillo, O.; Pedro, I.; Perez-Yañez, S.; Reyes, E. "Supramolecular Architectures based on p-Cymene/Ruthenium Complexes Functionalized with Nucleobases" CrystEngComm. 2017, 19, 6039-6048.
Villar, L.; Uria, U.; Martinez, J. I.; Prieto, L.; Reyes, E.; Carrillo, L.; Vicario, J. L. "Enantioselective Oxidative (4+3) Cycloaddition between Allenamides and Furans through Bifunctional H-bonding/Ion Pairing Interactions" Angew. Chem. Int. Ed. 2017, 56, 10535-10538 (Highligthed in Synfacts 2017, 13, 1093).
Prieto, L.; Sanchez-Diez, E.; Uria, U.; Reyes, E.; Carrillo, L.; Vicario, J. L. "Catalytic Generation of Donor-Acceptor Cyclopropanes under N-Heterocyclic Carbene Activation and their Stereoselective Reaction with Alkylideneoxindoles" Adv. Synth. Catal. 2017, 359, 1678-1683.
Orue, A.; Uria, U.; Roca-Lopez, D.; Delso, I.; Reyes, E.; Carrillo, L.; Merino, P.; Vicario, J. L. "Racemic Hemiacetals as Oxygen-Centered Pronucleophiles Triggering Cascade 1,4-Addition/Michael Reaction through Dynamic Kinetic Resolution under Iminium catalysis. Reaction Development and Mechanistic Insights" Chem. Sci. 2017, 8, 2904-2913.
Prieto, L.; Juste-Navarro, V.; Uria, U.; Delso, I.; Reyes, E.; Tejero, T.; Carrillo, L.; Merino, P.; Vicario, J. L. "Regioselectivity Change in the Organocatalytic Enantioselective (3+2) Cycloaddition with Nitrones Through Cooperative H-Bonding Catalysis/Iminium Activation" Chem. Eur. J. 2017, 23, 2764-2768.
Reyes, E.; Uria, U.; Vicario, J. L.; Carrillo, L. "Enantioselective Cascade Reactions under N-Heterocyclic carbene Catalysis" Synthesis 2017, 49, 451-471.

Publicaciones 2016

Publications 2016

Vicario, J. L. "Aminocatalytic Enantioselective Cycloadditions" Synlett 2016, 27, 1006-1021.
Roca Lopez, D.; Uria, U.; Reyes, E.; Carrillo, L.; Jorgensen, K. A.; Vicario, J. L.; Merino, P. "Mechanistic Insights in the Mode of Action of Bifunctional Pyrrolidine-Squaramide-derived Organocatalysts" Chem. Eur. J. 2016, 22, 884-889.
Riaño, I.; Diaz, E.; Uria, U.; Reyes, E.; Carrillo, L.; Vicario, J. L. "Organocatalytic Enantio- and Diastereoselective Synthesis of 3,5-Disubstituted Prolines" Chem. Commun. 2016, 52, 2330-2333.
Sanchez-Diez, E.; Vesga, D.; Reyes, E.; Uria, U.; Carrillo, L.; Vicario, J. L. "Organocatalytically Generated Donor−Acceptor Cyclopropanes in Domino Reactions. One-Step Enantioselective Synthesis of Pyrrolo[1,2-a]quinolines" Org. Lett. 2016, 16, 1270-1273.

Publicaciones 2015

Publications 2015

Martínez, J. I.; Uria, U.; Muñiz, M.; Reyes, E.; Carrillo, L.; Vicario, J. L. "Organocatalytic and Enantioselective Michael Reaction between α-Nitroesters and Nitroalkenes. Syn/anti-selectivity Control Using Catalysts with the Same Absolute Backbone Chirality" Beilstein J. Org. Chem. 2015, 11, 2577-2583.
Riano, I.; Uria, U.; Carrillo, L.; Reyes, E.; Vicario, J. L."4-Alkenyl-5H-1,2,3-oxathiazole 2,2-dioxides in Catalytic and Enantioselective [4 + 2] Cycloaddition through Iminium Activation. Straightforward Access to the trans-Decaline Framework and to Densely Functionalized Cyclohexanes" Org. Chem. Front. 2015, 2, 2016-210.
Orue, A.; Uria, U.; Reyes, E.; Carrillo, L.; Vicario, J. L. "Catalytic Enantioselective [5+2] Cycloaddition between Oxidopyrylium Ylides and Enals under Dienamine Activation" Angew. Chem. Int. Ed. 2015, 54, 3043-3046 (Highlighted in Synfacts 2015, 11, 433).
Sanchez-Diez, E.; Fernandez, M.; Uria, U.; Reyes, E.; Carrillo, L.; Vicario, J. L. "Enantioselective Synthesis of Tertiary Propargylic Alcohols under N-Heterocyclic Carbene Catalysis" Chem. Eur. J. 2015, 21, 8384-8388.
Ugarriza, I.; Uria, U.; Reyes, E.; Carrillo, L.; Vicario, J. L. "Organocatalytic Enantioselective [3+2] Cycloaddition of Azomethine Ylides and Acrolein" Asym. Catal. 2015, 2, 26-36.

Publicaciones 2014

Publications 2014

Reyes, E.; Uria, U.; Carrillo, L.; Vicario, J. L. "Transannular Reactions in Asymmetric Total Synthesis" Tetrahedron 2014, 70, 9461-9484.
Martinez, J. I.; Villar, L.; Uria, U.; Carrillo, L.; Reyes, E.; Vicario, J. L. "Bifunctional Squaramide Catalysts with the Same Absolute Chirality for the Diastereodivergent Access to Densely Functionalized Cyclohexanes through Enantioselective Domino Reactions. Synthesis and Mechanistic Studies" Adv. Synth. Catal. 2014, 356, 3627-3648.
Ugarriza, I.; Uria, U.; Carrillo, L.; Vicario, J. L.; Reyes, E. "Base Promoted C-N Acyl Rearrangement: an Unconventional Approach to alfa-AminoAcid Derivatives" Chem. Eur. J. 2014, 20, 11650-11654.
Alonso, B.; Uria, U.; Carrillo, L.; Vicario, J. L.; Reyes, E. "Base Free Catalyzed Enantioselective Michael Reaction of bis(phenylsulfonyl)methane to alfa,beta-Unsaturated Aldehydes under Iminium Activation" Curr. Top. Med. Chem. 2014, 12, 1317-1322.
Prieto, L.; Talavera, G.; Uria, U.; Reyes, E.; Vicario, J. L.; Carrillo, L. "Favoring Trienamine Activation through Unconjugated Dienals: Organocatalytic Enantioselective Remote Functionalization of Alkenes" Chem. Eur. J. 2014, 20, 2145-2148.
Fernandez, M.; Uria, U.; Orbe, L.; Vicario, J. L.; Reyes, E.; Carrillo, L. "Ethyl Glyoxylate N-Tosylhydrazone as Sulfonyl-Transfer Reagent in Base-Catalyzed Sulfa-Michael Reactions" J. Org. Chem. 2014, 79, 441-445.

Publicaciones 2013

Publictions 2013

Iza, A.; Uria, U.; Reyes, E.; Carrillo, L.; Vicario, J. L. "A General Approach for the Asymmetric Synthesis of Densely Substituted Piperidines and Fully Substituted Piperidinones Employing the Asymmetric Mannich Reaction as Key Step" RSC Adv. 2013, 3, 25800-25811.
Iza, A.; Ugarriza, I.; Uria, U.; Reyes, E.; Carrillo, L.; Vicario, J. L. "The Organocatalytic Enantioselective [3+2] Cycloaddition Reaction od alpha,beta-Unsaturated Aldehydes with Azomethine Ylides Applied to the Asymmetric Synthesis of Densely Substituted Pyrroloisoquinolines" Tetrahedron 2013, 69, 8878-8884.
Reboredo, S.; Vicario, J. L.; Carrillo, L.; Reyes, E.; Uria, U. "A Simple Synthesis of Polysubstituted Pyrrolidines by an Organocatalytic Three-Component Approach Featuring a One-Pot Condensation and [3+2]-Cycloaddition Reaction in Aqueous Medium" Synthesis 2013, 45, 2669-2678.
Martínez, J. I.; Reyes, E.; Uria, U.; Carrillo, L.; Vicario, J. L. "Optimizing the Structure of 4-Dialkylamino-alpha,alpha-diarylprolinol Ethers as Catalysts for the Enantioselective Cyclopropanation of alpha,beta-Unsaturated Aldehydes in Water" ChemCatChem 2013, 5, 2240-2247.
Alonso, B.; Ocejo, M.; Carrillo, L.; Vicario, J. L.; Reyes, E.; Uria, U. "Using Heteroaryl-lithium Reagents as Hydroxycarbonyl Anion Equivalents in Conjugate Addition Reactions with (S,S)-(+)-Pseudoephedrine as Chiral Auxiliary. Enantioselective Synthesis of 3-Substituted Pyrrolidines" J. Org. Chem. 2013, 78, 614-627.
Talavera, G.; Reyes, E.; Vicario, J. L.; Carrillo, L.; Uria, U. "Using Coveniently Designed alpha-Amino Ketones in Michael Reactions under Iminium Catalysis: Enantioselective Synthesis of gamma-Lactams and gamma-Amino-delta-keto Esters" Adv. Synth. Catal. 2013, 355, 653-658.

Publicaciones 2012

Publications 2012

Orue, A.; Reyes, E.; Vicario, J. L.; Carrillo, L.; Uria, U. "Enantio- and Diastereoselective Synthesis of Substituted Tetrahydro-1H-isochromanes through a Dinamic Kinetic Resolution Proceeding under Dienamine Catalysis" Org. Lett. 2012, 14, 3740-3743.
Fernández, M.; Uria, U.; Vicario, J. L.; Reyes, E.; Carrillo, L. "Enantioselective Conjugate Addition of Donor-Acceptor Hydrazones to alpha,beta-Unsaturated Aldehydes through formal Diaza-Ene Reaction. Access to 1,4-Dicarbonyl Compounds" J. Am. Chem. Soc. 2012, 134, 11872-11875 (Highligthed in Synfacts 2012, 8, 1147).
Reyes, E.; Fernández, M.; Uria, U.; Vicario, J. L.; Badía, D.; Carrillo, L. "Organocatalytic Enantioselective aza-Michael Reaction" Curr. Org. Chem. 2012, 15, 521-546.
Reboredo, S.; Reyes, E.; Vicario, J. L.; Badia, D.; Carrillo, L.; Cozar, A.; Cossio, F. P. "The Amine-Catalyzed Enantioselective [3+2] Cycloaddition of Azomethine Ylides with alpha,beta-Unsaturated Aldehydes. Applications and Mechanistic Implications" Chem. Eur. J. 2012, 18, 7179-7188.
Talavera, G.; Reyes, E.; Vicario, J. L.; Carrillo, L. "Cooperative Dienamine/Hydrogen-Bonding Catalysis: Enantioselective Formal [2+2] Cycloaddition of Enals with Nitroalkenes" Angew. Chem. Int. Ed. 2012, 51, 4104-4107 (Highligthed in Synfacts 2012, 8, 674 and Angew. Chem. Int. Ed. 2012, 51, 9734).
Fernández, M.; Vicario, J. L.; Reyes, E.; Carrillo, L.; Badía, D. "Organocatalytic Enantioselective Synthesis of 2,3-Dihydropyridazines" Chem. Commun. 2012, 48, 2092-2094.
Fernández, M.; Reyes, E.; Vicario, J. L.; Badía, D.; Carrillo, L. "Organocatalytic Enantioselective Synthesis of Pyrazolidines, Pyrazolines and Pyrazolidinones" Adv. Synth. Catal. 2012, 354, 371-376.

Publicaciones 2011

Publications 2011

Fernández, N.; Carrillo, L.; Vicario, J. L.; Badía, D.; Reyes, E. "Organocatalytic Enantioselective (3+2) Cycloaddition using Stable Azomethine Ylides" Chem. Commun. 2011, 47, 12313-12315.
Reboredo, S.; Vicario, J. L.; Badia, D.; Carrillo, L.; Reyes, E. "Complete 2,5-Diastereocontrol in the Organocatalytic Enantioselective [3+2] Cycloaddition of Enals with Azomethine" Adv. Synth. Catal. 2011, 353, 3307-3312.
Alonso, B.; Reyes, E.; Carrillo, L.; Vicario, J. L.; Badia, D. "Organocatalytic Enantioselective Formal Conjugate Addition of Hydroxymoyl Anion to alpha,beta-Unsaturated Aldehydes" Chem. Eur. J. 2011, 17, 6048-6051.
Reyes, E.; Ruiz, N.; Vicario, J. L.; Badía, D.; Carrillo, L. "Stereoselective Total Synthesis of (-)-beta-Conhydrine and (+)-alfa-Conhydrine" Synthesis 2011, 43, 443-450.
Ocejo, M.; Carrillo, L.; Vicario, J. L.; Badía, D.; Reyes, E. "Role of Pseudoephedrine as Chiral Auxiliary in the "Acetate-Type" Aldol Reaction with Chiral Aldehydes; Asymmetric Synthesis of Highly Functionalized Chiral Building Blocks" J. Org. Chem. 2011, 76, 460-470.
Uria, U.; Reyes, E.; Vicario, J. L.; Badía, D.; Carrillo, L. "5-Mercaptotetrazoles as Synthetic Equivalents of Nitrogen-Contaning Functional Groups. The Case of the Organocatalytic Enantioselective aza-Michael Reaction" Org. Lett. 2011, 13, 336-339.

Publicaciones 2010

Publications 2010

Uria, U.; Vicario, J.L.; Badia, D.; Carrillo, L.; Reyes, E.; Pesquera, A. "'On Water' Iminium/Enamine Catalysis: Organocatalytic Enantioselective Cyclopropanation of α,β-Unsaturated Aldehydes" Synthesis, 2010, 701-703.
Iza, Ainara; Carrillo, L.; Vicario, J. L.; Badia, D.; Reyes, E.; Martinez, J. I. "The Organocatalytic [3+2] Cycloaddition of Azomethine Ylides and α,β-Unsaturated Aldehydes as a Convenient Tool for the Enantioselective Synthesis of Pyrrolizidines and Indolizidines" Org. Biomol. Chem. 2010, 8, 2238-2244.
Vicario, J. L.; Badia, D. "Enantioselective 6 pi-Electrocyclizations: Pushing the Limits in Organocatalytic Pericyclic Reactions" ChemCatCem, 2010, 2, 375-378.

Publicaciones 2009

Publications 2009

Reyes, E.; Talavera, G.; Vicario, J.L.; Badia, D.; Carrillo, L. "Enantioselective Organocatalytic Domino Oxa-Michael/Aldol/Hemiacetalization: Synthesis of Polysubstituted Furofurans Containing Four Stereocenters" Angew. Chem. Int. Ed. 2009, 48, 5701-5704. (Highlighted in Synfacts 2009, 1032)
Ocejo, M.; Carrillo, L.; Badia, D.; Vicario, J. L.; Fernandez, N.; Reyes, E. "Highly Regio- and Stereoselective Addition of Organolithium Reagents to Extended Conjugate Amides Using (S,S)-(+)-Pseudoephedrine as Chiral Auxiliary" J. Org. Chem. 2009, 74, 4404-4407.

Publicaciones 2008

Publications 2008

Cabrera, S.; Reyes, E.; Aleman, J.; Milelli, A.; Kobbelgaard, A.; Jorgensen, K. A. "Organocatalytic Asymmetric Synthesis of α,α-Disubstituted α-Amino Acids and Derivatives" J. Am. Chem. Soc. 2008, 130, 12031-12037. (post-doc E.R.)
Aleman, J.; Milelli, A.; Cabrera, S.; Reyes, E.; Jorgensen, K. A. "Asymmetric 1,4-Addition of Oxazolones to Nitroalkenes, Bifunctional Cinchona Alkaloid Thiourea Organocatalysts: Synthesis of α,α-Disubstituted α-Amino Acids" Chem. Eur. J. 2008, 14, 10958-10966. (post-doc E.R.)
Ruiz, N.; Reyes, E.; Vicario, J. L.; Badia, D.; Carrillo, L.; Uria, U. "Organocatalytic Enantioselective Synthesis of Highly Functionalized Polysubstituted Pyrrolidines" Chem. Eur. J. 2008, 14, 9357-9367.
Ruiz, N.; Vicario, J. L.; Badía, L.; Carrillo, L.; Alonso, B. "(S,S)-(+)-Pseudoephedrine a-iminoglyoxylamide as a Chiral Glycine Cation Equivalent. A Modular and Flexible Approach to Enantioenriched a-Amino Ketones" Org. Lett. 2008, 10, 2613-2626.
Badía, D.; Carrillo, L.; Vicario, J. L. "Adiciones Conjugadas Estereocontroladas. Desde el Uso de Auxiliares Quirales a la Organocatálisis Asimétrica" An. Quím. 2008, 104, 189-196. (Languaje: Spanish)

Publicaciones 2007

Publications 2007

Reyes, E.; Jiang, H.; Milelli, A.; Elsner, P.; Hazell, R. G.; Jorgensen, K. A. "How to Make Five Contiguous Stereocenters in one Reaction: Asymmetric Organocatalytic Synthesis of Pentasubstituted Cyclohexanes" Angew. Chem. Int. Ed. 2007, 46, 9202-9205. (Highlighted in Synfacts 2008, 89). (Post-doc E.R.)
Vicario, J. L.; Reboredo, S.; Badia, D.; Carrillo, L. "Organocatalytic Enantioselective [3+2] Cycloaddition of Azomethine Ylides and a,b-Unsaturated Aldehydes" Angew. Chem. Int. Ed. 2007, 46, 5168-5172. (Highlighted in Synfacts 2007, 873)
Vicario, J. L.; Badia, D.; Carrillo, L. "Organocatalytic Enantioselective Michael and Hetero-Michael Reactions" Synthesis. 2007, 2065-2092.
Aleman, J.; Reyes, E.; Richter, B.; Overgaard, J.; Jorgensen, K. A. "Organocatalytic Asymmetric "anti-Michael" Reaction of β-Ketoesters" Chem. Comm. 2007, 3921-3823. (Post-doc E.R.)
Uria, U.; Vicario, J. L.; Badia, D.; Carrillo, L. "Organocatalytic Enantioselective Aza-Michael Reaction of Nitrogen Heterocycles and a,b-Unsaturated Aldehydes" Chem. Comm. 2007, 2509-2511.
Etxebarria, J.; Vicario, J. L.; Badía, D.; Carrillo, L. "A General and Enantiodivergent Method for the Asymmetric Synthesis of Piperidine Alkaloids: Concise Synthesis of (R)-Pipecoline, (S)-Coniine and other 2-Alkylpiperidines" Tetrahedron 2007, 63, 11421.

Publicaciones 2006

Publications 2006

Iza, A.; Vicario, J. L.; Carrillo, L.; Badia, D. "(+)-(S,S)-Pseudoephedrine as a Chiral Auxiliary in Asymmetric Mannich Reactions: Scope and Limitations" Synthesis 2006, 23, 4065-4074.
Reyes, E.; Vicario, J. L.; Badia, D.; Carrillo, L. "Organocatalytic Asymmetric Michael Addition of Aldehydes to b-Nitroacrolein Dimethyl Acetal" Org. Lett. 2006, 8, 6135-6138.
Reyes, E.; Vicario, J. L.; Carrillo, L.; Badia, D.; Uria, U.; Iza, A. "(S,S)-(+)-Pseudoephedrine as Chiral Auxiliary in Asymmetric Conjugate Addition and Tandem Conjugate Addition/α-Alkylation Reactions" J. Org. Chem. 2006, 71, 7763-7772.
Reyes, E.; Vicario, J. L.; Carrillo, L.; Badia, D.; Iza, A.; Uria, U. "Tandem Asymmetric Conjugate Addition/α-Alkylation Using (S,S)-(+)-Pseudoephedrine as Chiral Auxiliary" Org. Lett. 2006, 8, 2535-2538.

Publicaciones 2005

Publications 2005

Vicario, J. L.; Badia, D.; Carrillo, L.; Etxebarria, J.; Reyes, E.; Ruiz, N. "The Asymmetric aza-Michael Reaction. A Review" Org. Prep. Proc. Int. 2005, 37, 513-538.
Etxebarria, J.; Vicario, J. L.; Badia, D.; Carrillo, L.; Ruiz, N. "(S,S)-(+)-Pseudoephedrine as Chiral Auxiliary in Asymmetric aza-Michael Reactions. Unexpected Selectivity Change when Manipulating the Structure of the Auxiliary" J. Org. Chem. 2005, 70, 8790-8800.
Ocejo, M.; Vicario, J. L.; Badia, D.; Carrillo, L.; Reyes, E. "A direct and Efficient Stereoconservative Procedure for the Selective Oxidation of N-Protected β-Amino Alcohols" Synlett 2005, 2110-2112.
Rodriguez, M.; Vicario, J. L.; Badia, D.; Carrillo, L. "(S,S)-(+)-Pseudoephedrine as Chiral Auxiliary in Asymmetric Acetate Aldol Reactions" Org. Biomol. Chem. 2005, 3, 2026-2030.
Vicario, J. L.; Badia, D.; Carrillo, L.; Reyes, E.; Etxebarria, J. "α-Amino Acids, β-Amino Alcohols and Related Compounds as Chiral Auxiliaries, Ligands and Catalysts in the Asymmetric Aldol Reaction" Curr. Org. Chem. 2005, 9, 219-235.

Publicaciones 2004

Publications 2004

Reyes, E.; Carrillo, L.; Vicario, J. L.; Badía, D. "Asymmetric Hydroxylation of (S,S)-(+)-Pseudephedrine Phenylacetamide Enolates" Lett. Org. Chem. 2004, 1, 331-334.
Echeberría, J.; Vicario, J. L.; Badia, D.; Carrillo, L. "Asymmetric Synthesis of b-Amino Esters by aza-Michael Reaction of a,b-Unsaturated Amides Using (S,S)-(+)-Pseudoephedrine as chiral auxiliary" J. Org. Chem. 2004, 69, 2588-2591.
Vicario, J. L.; Rodriguez, M.; Badia, D.; Carrillo, L.; Reyes, E. "Double Stereodifferentiation in the "Acetate-Type" Aldol Reaction with Garner`s Aldehyde. Stereocontrolled Synthesis of Polihydroxylated g-Amino Carbonyl Compounds" Org. Lett. 2004, 6, 3171-3174.
Anakabe, E.; Carrillo, L.; Vicario, J. L.; Badía, D. "Steroselective Synthesis of Aporphine Alkaloids Using a Hypervalent Iodine (III) Reagent-Promoted Oxidative Nonphenolic Biaryl Coupling Reaction. Total Synthesis of (S)-(+)-Glaucine" Synthesis, 2004, 1093-1097

Nested Applications

Publications 2025

Publicaciones 2024

Publicaciones 2023

Publicaciones 2022

Publicaciones 2021

Publicaciones 2020

Publicaciones 2019

Publicaciones 2018

Publicaciones 2017

Publicaciones 2016

Publicaciones 2015

Publicaciones 2014

Publicaciones 2013

Publicaciones 2012

Publicaciones 2011

Publicaciones 2010

Publicaciones 2009

Publicaciones 2008

Publicaciones 2007

Publicaciones 2006

Publicaciones 2005

Publicaciones 2004