Patents

NUCLEIC ACID MOLECULE, FUSION PROTEIN AND METHOD FOR ALTERING THE GENETIC MATERIAL OF A CELL

Type:
Patent
Researcher(s):
GAINZA LAFUENTE EUSEBIO; GAINZA LUCEA GARAZI; DEL POZO PEREZ ANGEL; PASTOR NAVARRO MARTA; PEDRAZ MUNOZ JOSÉ LUIS; VINAS CIORDIA MIGUEL; BACHILLER PEREZ DANIEL; GALVEZ JEREZ VICTOR.
Year:
2015
Description:

The invention relates to a nucleic acid molecule encoding a fusion protein, said nucleic acid molecule comprising, in transcription direction 5 ́---3 ́, at least: one nucleic acid sequence encoding a DNA-binding domain; and a nucleic acid sequence encoding a FokI-type catalytic domain, the 3\' end thereof comprising a nucleic acid sequence encoding a peptide comprising between 18 and 23 amino acids. The invention also relates to a fusion protein that can be obtained, for example, from the transcription of said molecule, and to a method for altering the genetic material of a cell using said molecule or protein.

Link with additional information:
https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20161220&DB=&locale=en_EP&CC=ES&NR=2594486A1&KC=A1&ND=4#