Grupo de Investigación en Neuropsicofarmacología

• Bagán A, López-Ruiz A, Abás S, Molins E, Pérez B, Muneta-Arrate I, Callado LF, Escolano C  Synthesis of Diversely Substituted Diethyl (Pyrrolidin-2-Yl)Phosphonates Molecules,  2025;  30(9):2078
• Bagán A, López-Ruiz A, Abás S, Ruiz-Cantero MC, Vasilopoulou F, Taboada-Jara T, Griñán-Ferré C, Pallàs M, Muguruza C, Diez-Alarcia R, Callado LF, Entrena JM, Cobos EJ, Pérez B, Morales-García JA, Molins E, De Jonghe S, Daelemans D, Brea J, Val C, Loza MI, Hernández-Hernández E, García-Sevilla JA, García-Fuster MJ, Díaz C, Fernández-Godino R, Genilloud O, Beljkaš M, Oljačić S, Nikolic K, Escolano C.  Discovery of (3-Phenylcarbamoyl-3,4-dihydro-2 H-pyrrol-2-yl)phosphonates as Imidazoline I2 Receptor Ligands with Anti-Alzheimer and Analgesic Properties Journal of Medicinal Chemistry,  2025;  68(3),  2551 - 2573
• Díaz-Pons A, Castaño-Castaño S, Ortiz-García de la Foz V, Yorca-Ruiz Á, Martínez-Asensi C, Munarriz-Cuezva E, Ayesa-Arriola R.  Understanding the potential impact of trimester-specific maternal immune activation due to SARS-CoV-2 on early human neurodevelopment and the role of cytokine balance Brain, Behavior, and Immunity - Health,  2025;  44:100956
• Erkizia-Santamaria I, Meana JJ, Ortega JE.  Preclinical drug development: Seeking to improve the reproducibility of results from behavioural experiments in animals European Neuropsychopharmacology,  2025;  95,  2 - 3
• Erkizia-Santamaría I, Horrillo I, Martínez-Álvarez N, Pérez-Martínez D, Rivero G, Erdozain AM, Meana JJ, Ortega JE  Evaluation of behavioural and neurochemical effects of psilocybin in mice subjected to chronic unpredictable mild stress Translational Psychiatry,  2025;  15(1):201
• Erkizia-Santamaría I, Horrillo I, Meana JJ, Ortega JE.  Clinical and preclinical evidence of psilocybin as antidepressant. A narrative review Progress in Neuro-Psychopharmacology & Biological Psychiatry,  2025;  136:111249
• Erkizia-Santamaría I, Martínez-Álvarez N, Salinas-Novoa L, Meana JJ, Ortega JE  Role of endogenous serotonin in psychedelic-like effects of psilocybin in mice International Journal of Neuropsychopharmacology,  2025;  28(6):pyaf035
• Hernández-Hernández E, Petyuk VA, Valor-Blanquer J, Yáñez-Gómez F, Barr AM, De Jager PL, Chen EY, Leurgans SE, Schneider JA, Bennett DA, Honer WG, García-Fuster MJ, Ramos-Miguel A  Contributions of major tau kinase activation and phospho-tau accumulation to cortical and hippocampal tangle formation and cognition in older adults Neurobiology of Disease,  2025;  210:106924
• Marques BL, Lirio PHC, Vicente MA, Unzueta-Larrinaga P, Urigüen L, Campos AC  Cannabinoids and Extracellular Vesicles as Potential Biomarkers and Therapeutic Targets in Neuropsychiatric Disorders: A Hypothesis-Driven Review Pharmaceuticals,  2025;  18(12):1817
• Martínez-Peula O, Ramos-Miguel A, Muguruza C, Callado LF, Meana JJ, Rivero G.  A method for HDAC activity screening in postmortem human brain. A proof-of-concept study with antipsychotics Journal of Neuroscience Methods,  2025;  416:110365
• Mas S, Elcoroaristizabal-Martín X, Cortijo Bringas C, Morentin B, Callado LF, Meana JJ, Rivero G  Altered immune and inflammatory gene expression in prefrontal cortex of antipsychotic-free schizophrenia subjects Brain, Behavior, & Immunity - Health,  2025;  49:101125
• Miquel-Rio L, Jericó-Escolar J, Yanes-Castilla C, Sarriés-Serrano U, Paz V, Callado LF, Meana JJ, Bortolozzi A  A molecular convergence in the triad of parkinson's disease, depressive disorder and gut health is revealed by the inflammation-miRNA axis Journal of Neuroinflammation,  2025;  22(1):260
• Miranda-Azpiazu P, Muguruza C, Stepniewski TM, Muneta-Arrate I, Moreira D, Brea J, Callado LF, Loza MI, González-Maeso J, Selent J, Diez-Alarcia R, Meana JJ  Distinctive patterns of G protein coupling induced by the structurally similar 5-HT2A receptor ligands ketanserin and altanserin in human prefrontal cortex Molecular Pharmacology,  2025;  107(11):100075
• Morentin B, Oraa R, Javier Meana J, Callado LF  Assessment of risk factors associated with methadone-induced deaths: A population study based on forensic autopsies (2003-2022) Forensic Science International,  2025;  376:112604
• Munarriz-Cuezva E, Meana JJ.  Poly (I:C)-induced maternal immune activation generates impairment of reversal learning performance in offspring Journal of Neurochemistry,  2025;  169(1):e16212
• Muneta-Arrate I, Di Pizio A, Selent J, Diez-Alarcia R  The complexity of G protein-coupled receptor (GPCR) modulation and signaling British Journal of Pharmacology,  2025;  182(14),  3039 - 3043
• Muneta-Arrate I, Miranda-Azpiazu P, Horrillo I, Diez-Alarcia R, Meana JJ.  Ligand bias and inverse agonism on 5-HT2A receptor-mediated modulation of G protein activity in post-mortem human brain British Journal of Pharmacology (prentsan),  2025
• Odagaki Y, Kinoshita M, Honda M, Meana JJ, Callado LF, García-Sevilla JA, Palkovits M, Borroto-Escuela DO, Fuxe K  Receptor-mediated Gi-3 activation in mammalian and human brain membranes: Reestablishment method and its application to nociceptin/orphanin FQ opioid peptide (NOP) receptor/Gi-3 interaction Journal of Pharmacological Sciences,  2025;  158(2),  131 - 138
• Olazagoitia-Garmendia A, Rojas-Márquez H, Trobisch T, Moreno-Castro C, Rodriguez Etxebarria A, Mentxaka J, Tripathi A, Yang B, Martin Ruiz I, Anguita J, Meana JJ, Ding Y, Dutta R, Schirmer L, Igoillo-Esteve M, Santin I, Castellanos-Rubio A  An inflammation-associated lncRNA induces neuronal damage via mitochondrial dysfunction Molecular Therapy Nucleic Acids,  2025;  36(2): 102533
• Prohens L, Rodríguez N, Segura ÀG, Martínez-Pinteño A, Olivares-Berjaga D, Martínez I, Mezquida G, Santas-Martín JA, Morentin B, Meana JJ, Callado LF, Gassó P, Rivero G, Mas S  Association of astrocyte-specific gene expression in the dorsolateral prefrontal cortex with clozapine treatment in schizophrenia Translational Psychiatry,  2025;  15(1):458