Copper-catalyzed asymmetric conjugate addition of diethylzinc to α,β-unsaturated imines derived from α-aminoacids. Enantioselective synthesis of γ-substituted α-dehydroaminoesters
- Autoría:
- Francisco Palacios, Javier Vicario
- Año:
- 2006
- Revista:
- Organic Letters
- Volumen:
- 8
- Página de inicio - Página de fin:
- 5405 - 5408
- Descripción:
-
A highly enantioselective synthesis of α-dehydroaminoacids with a stereogenic center in the γ position through copper-catalyzed asymmetric conjugate addition of diethylzinc to α,β-unsaturated imines using a TADDOL-derived phosphoramidite complex is reported