Grupo de Investigación Síntesis Orgánica en Química Médica (OSMC)

• Raslan, A.; Saenz del Burgo, L.; Espona-Noguera, A.; Ochoa de Retana, A. M.; Sanjuan, M.L.; Canibano-Hernández, A.; Gálvez-Martín, P.; Ciriza, J.; Pedraz, J.L.  BSA- and Elastin-Coated GO, but Not Collagen-Coated GO, Enhance the Biological Performance of Alginate Hydrogels Pharmaceutics,  2020;  12,  543 - 563
• Carraminana, V.; Ochoa de Retana,A. M.; de los Santos, J.M.; Palacios, F.  First synthesis of merged hybrids phosphorylated azirino[2,1-b]benzo [e][1,3]oxazine derivatives as anticancer agents European Journal of Medicinal Chemistry,  2020;  185,  111771 - 111781
• C. Masdeu, M. Fuertes, E. Martin-Encinas, A. Selas, C. Rubiales, F. Palacios, C. Alonso  Fused 1,5 Naphthyridines: Synthetic tools and applications Molecules,  2020;  25,  3508 - 3562
• Alonso, C.; de los Santos, J.M.; Palacios, F.  New Challenges in Drug Discovery - July 8-11, 2019, Vitoria-Gasteiz, Spain ChemMedChem,  2020;  15,  168 - 171
• Martin-Encinas, E.; Conejo-Rodriguez, V.; Miguel, J.A.; Martínez-Ilarduya, J.M.; Rubiales, G.; Knudsen, B. R.; Palacios, F.; Alonso, C.  Novel phosphine sulphide gold(i) complexes: topoisomerase I inhibitors and antiproliferative agents Dalton Transactions,  2020;  49,  7852 - 7861
• V. Carramiñana, Ana M. Ochoa de Retana, F. Palacios, J M de los Santos  Synthesis of alpha-aminophosphonic acid derivativers through ther addition of O- and S-nucleophiles to 2H-azirines and their antiproliferative effect on A549 human lung adenocarcinoma cells Molecules,  2020;  25,  3332 - 3359
• Martin-Encinas, E.; Selas, A.; Tesauro, C.; Rubiales, G.; Knudsen, B.R.; Palacios, F.; Alonso, C.  Synthesis of novel hybrid quinolino[4,3-b][1,5]naphthyridines and quinolino[4,3-b][1,5]naphthyridin-6(5H)-one derivatives and biological evaluation as topoisomerase I inhibitors and antiproliferatives European Journal of Medicinal Chemistry,  2020;  195,  112292 - 112301
• M. Fuertes, C. Masdeu, E. Martin-Encinas, A. Selas, C. Rubiales, F. Palacios, C. Alonso  Synthesis strategies, reactivity and applications of 1,5Naphthyridines Molecules,  2020;  25,  3252 - 3324
• del Corte, X.; Martinez de Marigorta, E.; Palacios, F.; Vicario, J.  A Bronsted Acid-Catalyzed Multicomponent Reaction for the Synthesis of Highly Functionalized gamma-Lactam Derivatives Molecules,  2019;  24,  2951 - 2964
• Tejeria, A.; Perez-Pertejo, Y.; Reguera, R. M.; Carbajo-Andrés, R.; Balaña-Fouce, R.; Alonso, C.; Martín-Encinas, E; Selas, A.; Rubiales, G.; Palacios, F.  Antileishmanial activity of new hybrid tetrahydroquinoline and quinoline derivatives with phosphorus substituents European Journal of Medicinal Chemistry,  2019;  168,  18 - 31
• Maestro, A.; Martinez de Marigorta, E.; Palacios, F.; Vicario, J.  Enantioselective alpha-Aminophosphonate Functionalization of Indole Ring through an Organocatalyzed Friedel-Crafts Reaction Journal of Organic Chemistry,  2019;  84,  1094 - 1102
• Maestro, A.; Martínez de Marigorta, E.; Palacios, F.; Vicario, J.  Enantioselective Aza-Reformatsky Reaction with Ketimines Organic Letters,  2019;  21,  9473 - 9477
• Maestro, A.; del Corte, X.; Martinez de Marigorta, E.; Palacios, F.; Vicario, J.  Enantioselective synthesis of functionalized alpha alpha-aminophosphonic acid derivatives Phosphorus Sulfur and Silicon and the Related Elements,  2019;  194,  287 - 291
• Martinez de Marigorta, E.; de los Santos, J. M.; Ochoa de Retana, A. M..; Vicario, J.; Palacios, F.  Multicomponent reactions (MCRs): a useful access to the synthesis of benzo-fused gamma-lactams Tipo de publicación Beilstein Journal of Organic Chemistry,  2019;  15,  1065 - 1085
• Grosso, C.; Brigas, A.; de los Santos, J. M.; Palacios, F.; Lemos, A.; Pinho e Melo, T. M. V. D.  Natural deep eutectic solvents in the hetero-Diels-Alder approach to bis(indolyl)methanes Monatshefte fur Chemie,  2019;  150,  1275 - 1288
• de los Santos, J.M.; Rubiales, G.; Es Sbai, Z. Carraminana, V,; Ochoa de Retana, A. M.; Palacios, F.  Reaction of phosphinyl nitrosoalkenes with electron-rich heterocycles Phosphorus Sulfur and Silicon and the Related Elements,  2019;  194,  545 - 549
• Martin-Encinas, E.; Rubiales, G.; Knudssen, B. R.; Palacios, F.; Alonso, C.  Straightforward synthesis and biological evaluation as topoisomerase I inhibitors and antiproliferative agents of hybrid Chromeno[4,3-b][1,5]Naphthyridines and Chromeno[4,3-b][1,5]Naphthyridin-6-ones European Journal of Medicinal Chemistry,  2019;  178,  752 - 766
• Carraminana, V.; Ochoa de Retana, A. M.; Vélez del Burgo, A.; de los Santos, J.M.; Palacios, F.  Synthesis and biological evaluation of cyanoaziridine phosphine oxides and phosphonates with antiproliferative activity European Journal of Medicinal Chemistry,  2019;  163,  736 - 746
• J. M. de los Santos, A. M. Ochoa de Retana, E. Mz de Marigorta, J. Vicario, F. Palacios  Catalytic Asymmetric Darzens and Aza-Darzens Reactions for the Synthesis of Chiral Epoxides and Aziridines ChemCatChem,,  2018;  10,  5092 - 5114
• A. Maestro, X. del Corte; E. Mz de Marigorta, F. Palacios, J. Vicario  Enantioselective synthesis of functionalized alpha-aminophosphonic acid derivatives Phosphorus Sulfur and Silicon and the Related Elements,  2018;  287 - 291