w_Vías de ubiquitinación neuronal y proteómica

Neuronal Ubiquitin Pathways and Proteomics


Department (s)
Biochemistry and Molecular Biology

Knowledge area
Biochemistry, Biomedicine and Renewable Energies
PI: Ugo Mayor Co-PI: Jesus M. Arizmendi and Nerea Osinalde


Ugo Mayor (Principal Investigator)

Benoit Lectez, Juanma Ramirez, Teresa García, Aitor Martínez, Natalia Presa (Posdoctoral researchers)
Nagore Elu, Unai Alduntzin, Cristina García (Predoctoral researchers)
Nerea Osinalde (Assistant Professor)
Jesus M. Arizmedi, Miren Josu Omaetxebarria (Associate Professor)
Jabi Beaskoetxea (Contracted research staff)


Ubiquitin, Proteomics, Angelman Syndrome, Parkinson, H2 production


We are a multidisciplinary research group with expertise in Molecular and Cellular Biology, Proteomics and Bioinformatics, and we work with cellular and animal models (flies and mice). The group is composed by an Ikerbasque research proffesor, 3 university professors, a technician, 5 postdoctoral researchers and 3 predoctoral researchers; financed by national and international entities.

Our main research line focuses on the proteomics characterization of ubiquitination on neuronal proteins involved in Angelman Syndrome and Parkinson disease, as well on studying the effects of such ubiquitinations. Additionally, we have recently initiated a new research line that aims to characterize the proteome changes associated with the production of H2 in the algae family Chlamydomonas, in order to  improve the produciton of this clean and revewable energy source.

Research lines

  1. Unraveling the molecular mechanisms involved in Angelman Syndrome and Parkinson Disease
  2. Identification of deubiquitinase substrates
  3. Characterization of the cellular pathways activating in the unicellular algae Chlamydomonas reinhardtii when H2 production is induced


  • Cabinets and incubators for cell culture
  • Gel documentation systems
  • Others

Website link