CONGRATULATIONS JANIRE!

Janire Saez, Ikerbasque Research Fellow in the Microfluidics Cluster UPV/EHU has recently published a paper in Advanced Healthcare Materials (IF: 10.26) in collaboration with Prof. Roisin Owens (University of Cambridge) and Dr. Francesco Tamagnini (University of Reading).

The paper describes the development of conducting scaffolds that resemble the extracellular matrix for the 3D cell culture and differentiation of SH-SY5Y human neuroblastoma cells. Recordings acquired through whole-cell patch-clamp from differentiated SHSY5Y cells in the scaffolds demonstrate that ECM constituents promote neuronal differentiation in situ. These findings reinforce the usability of 3D conducting supports as engineered highly biomimetic and functional in vitro tissue-like platforms for drug or disease modeling.