Cell Membrane Organization and Dynamics
| Departamento(s) Biochemistry and molecular Biology department |
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| Área(s) de la ciencia Biophysics |
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| IP: Adai Colom | Co-IP: | |
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Miembros Adai Colom / Marián Alonso / Andrea Merino |
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Palabras Clave Cell membrane biophysics, protein dynamics, HS-AFM, FLIM |
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Descripción Description (800 characters maximum): We aim to understand the role of membrane mechanics and protein dynamic involve in different cell process, especially, we are focus on immunological synapse, viral infection and ebriogenesis. We use a wide range of systems (in-vitro to embryos) and technics, particularly HS-AFM and Fast-FLIM. Objectives: 1-A new approach to study the mechanochemistry of cellular processes at high spatio-tempral resolution. 2-Measure the forces involved during embryogenesis and tissue-tissue communication. 3-Insight on the spatiotemporal organization and mechanics of protein complexes during the formation of the immunological synapse and viral infection. 4- Apply our technology, especially FAST-FLIM, as a fast and cheap diagnosis tool in infection and tumorigenesis. |
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