Subject

XSL Content

Cellular-Molecular Biology of Membranes

General details of the subject

Mode
Face-to-face degree course
Language
English

Teaching staff

NameInstitutionCategoryDoctorTeaching profileAreaE-mail
ALONSO IZQUIERDO, ALICIAUniversity of the Basque CountryProfesorado Catedratico De UniversidadDoctorNot bilingualBiochemistry and Molecular Biologyalicia.alonso@ehu.eus
COLOM DIEGO, ADAIUniversity of the Basque CountryInvestigador Ramón Y CajalDoctorNot bilingual** n o c o n s t a e l a r e a * ó " á r e a p r o v i s i o n a l"adai.colom@ehu.eus
CONTRERAS GOMEZ, XABIERUniversity of the Basque CountryVisitante IkerbaskeDoctorNot bilingualBiochemistry and Molecular Biologyxabier.contreras@ehu.eus
ETXANIZ IRIONDO, ASIERUniversity of the Basque CountryProfesorado Adjunto (Ayudante Doctor/A)DoctorBilingualBiochemistry and Molecular Biologyasier.echaniz@ehu.eus
GOÑI URCELAY, FELIX MARIAUniversity of the Basque CountryProfesorado Emerito UniversidadDoctorNot bilingualBiochemistry and Molecular Biologyfelix.goni@ehu.eus
JIMENEZ ROJO, NOEMIUniversity of the Basque CountryDoctorNot bilingual** n o c o n s t a e l a r e a * ó " á r e a p r o v i s i o n a l"noemi.jimenez@ehu.eus
LANDETA DIAZ, OLATZUniversity of the Basque CountryProfesorado Adjunto (Ayudante Doctor/A)DoctorBilingualBiochemistry and Molecular Biologyolatz.landeta@ehu.eus
MARTIN PLAGARO, CESAR AUGUSTOUniversity of the Basque CountryProfesorado PlenoDoctorBilingualBiochemistry and Molecular Biologycesar.martin@ehu.eus
MONTES BURGOS, LIDIA RUTHUniversity of the Basque CountryProfesorado Titular De UniversidadDoctorBilingualBiochemistry and Molecular Biologylidiaruth.montes@ehu.eus
NIETO GARAI, JON ANDERUniversity of the Basque CountryProfesorado Adjunto (Ayudante Doctor/A)DoctorBilingualBiochemistry and Molecular Biologyjonander.nieto@ehu.eus
RUIZ MIRAZO, KEPAUniversity of the Basque CountryPersonal Doctor InvestigadorDoctorNot bilingualLogic and Philosophy of Sciencekepa.ruiz-mirazo@ehu.eus
TERRONES URIO, OIHANAUniversity of the Basque CountryProfesorado AgregadoDoctorBilingualBiochemistry and Molecular Biologyoihana.terrones@ehu.eus

Study types

TypeFace-to-face hoursNon face-to-face hoursTotal hours
Lecture-based253863
Seminar253762

Ordinary call: orientations and renunciation

The evaluation of the course will be based on the following aspects:

1. Attendance and participation in class 50% of the final grade. 80% class attendance is required.

2. Scientific report 50% of the final grade.





This method of assessment could be changed if the guidelines of the health authorities so provide. The appropriate modifications would be announced in due course, with the necessary strategies and tools to guarantee the right of the student to be evaluated with equity and fairness.

Extraordinary call: orientations and renunciation

Written proof of the entire course program.





This method of assessment could be changed if the guidelines of the health authorities so provide. The appropriate modifications would be announced in due course, with the necessary strategies and tools to guarantee the right of the student to be evaluated with equity and fairness.

Temary

1. INTRODUCTION: RECENT ADVANCES IN MEMBRANE STUDIES.

2. THE ORIGIN OF CELL MEMBRANES

3. DEALING WITH MEMBRANE PROTEINS: THEIR PURIFICATION AND RECONSTITUTION.

4. "FUSIÓN DEL VIRUS DEL SIDA Y POSIBLE DEPENDENCIA DE LA COMPOSICIÓN DE MEMBRANA"

5. CRYO-ELECTRON MICROSCOPY: EXAMINING INTACT BIOLOGICAL MEMBRANES.

6. DETERGENTS: WASHING THE DISHES AND BEYOND

7. HOW NAKED VIRUSES ENTER THROUGH CELL MEMBRANES.

8. ANTICUERPOS NEUTRALIZANTES ANTI-MPER Y SU APLICACIÓN AL DESARROLLO DE VACUNAS ANTI-SIDA

9. BIOGENESIS OF CELL MEMBRANES

10. HOW BACTERIA ENTER THROUGH CELL MEMBRANES.

The case of B. pertussis (whopping cough) ATX toxin.

11. CELL AUTOPHAGY:MIMICKING THE NASCENT AUTOPHAGOSOME.

12. THE MOLECULAR MECHANISMS OF APOPTOSIS.

13. FLUORESCENCE IMAGING: EXPLORING THE FRONTIERS OF A RAPIDLY DEVELOPING TECHNIQUE.

14. MEMBRANE FISSION AND CURVATURE-SENSING PROTEINS

15. NUCLEAR MEMBRANES.

16. DYNAMICS AND RESOLUTION OF THE NUCLEOPLASMIC RETICULUM (Bioforo Special Lecture)

17. DRUG DELIVERY USING NANOPARTICLES.

18. LIPIDOMIC STUDIES OF CELL MEMBRANES.

Bibliography

Compulsory materials

For each session included in the programme, teachers will provide the student with additional teaching materials (i.e. PowerPoint presentations and other specialised references such as reviews or research articles) using the Egela digital platform.

Basic bibliography

The Biophysics of Cell Membranes. Biological Consequences. Editors: Epand, Richard M., Ruysschaert, Jean-Marie (Eds.) Springer, New York. (2017) ISBN 978-981-10-6244-5

The Structure of Biological Membranes (3rd ed.) Philip Y. Yeagle. CRC Press, Boca Raton FL, (2011). ISBN: 9781439809570

Cell Membranes . Lukas Buehler. Garland Science, New York. (2015) ISBN: 978-0815341963.

Membrane Structural Biology with Biochemical and Biophysical Foundations (2nd ed.). Mary Luckey. Garland Science, New York. (2014). ISBN: 978-1107030633.

Molecular Biology of the Cell (6th ed.) Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter (eds.) . Garland Science, New York. (2014). ISBN: 9780815344322

Membrane Protein Crystallization and Purification (2nd ed.). Carola Hunte, Gebhard von Jagow and Hermann Schagger (eds). Academic Press, Amsterdam. (2003). ISBN: 0-12-361776-6



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