Learning outcomes of the subject

The student will acquire a critical scientific spirit, capacity for experimental design and scientific communication in the field of Cell and Developmental Biology.

The student will acquire practical skills in the appropriate techniques to address problems of a basic or applied nature in Cell and Developmental Biology.

The student will acquire the knowledge, skills and abilities necessary to carry out an innovative research project in Cell and Developmental Biology.

The student will know how to apply advanced knowledge and techniques in Biochemistry and Molecular Biology to the study and understanding of cellular and developmental processes.

The student will acquire the self-learning skills that will make possible a continuous update in the methodological and conceptual advances in Cell and Developmental Biology.

Ordinary call: orientations and renunciation

Attendance is compulsory. Excused absences may be made up with the activity indicated by the person in charge of the session.



The intervention of the student in the classes will be valued, the questions and comments made in each session will be valued. A high participation and attendance to 100% of the sessions allows to pass the course.



An unexcused attendance of less than 80% of the sessions will result in the failure of the course.

In the case of absence with a justified cause (more than 30%), an exam/test of the subject adjusted to the specific situation will be carried out.



The evaluation tests of the course will be adjusted to the characteristics of the group and will be made explicit at the beginning of the course.





This method of assessment could be changed if the guidelines of the health authorities so provide. The appropriate modifications would be announced in due course, with the necessary strategies and tools to guarantee the right of the student to be evaluated with equity and fairness.





This method of assessment could be changed if the guidelines of the health authorities so provide. The appropriate modifications would be announced in due course, with the necessary strategies and tools to guarantee the right of the student to be evaluated with equity and fairness.

Extraordinary call: orientations and renunciation

The extraordinary call will involve the realization of an exam/test of the subject that will consist of the development of a topic of the subject to choose between two chosen at random.

Temary

Item 1 FUNDAMENTALS OF THE ORGANIZATION OF THE EUKARYOTIC CELL

Item 2 CELLULAR BASES OF TRANSCRIPTION

Item 3 CELLULAR BASES OF NUCLEAR pre-mRNA PROCESSING

Item 4 CELLULAR BASES OF SYNTHESIS AND RNA PROCESSING: NUCLEOLUS

Item 5 CELLULAR BASES OF THE UBIQUITINE-PROTEASOME NETWORK ORGANIZATION

Item 6 NORMAL CELLS VS TUMOR CELLS

Item 7 HEMATOENCEPHALIC BARRIER CELL BIOLOGY (BHE)

Item 8 CELL BIOLOGY OF BLOOD-BARRIER CEFALORRACHIDES (CSF)

Item 9 INTRACEREBRAL CELL AND TISSUE TRANSPLANTS: APPLICATION TO THE STUDY OF ANGIOGENESIS AND THE HEMATOENCHEPHALIC BARRIER (BHE)

Item 10 "IN VITRO" AGING

Item 11 "LIVE" AGEING

Item 12 AGEING BIOMARKERS

Item 13 INTRODUCTION TO EMBRIONARY DEVELOPMENT MODELS OF EMBRYONIC DEVELOPMENT. EARLY STAGES OF EMBRYONIC DEVELOPMENT

Item 14 SPECIFICATION OF PRIMARY EMBRYOUS AXES

Item 15 REGULATION OF GENIC EXPRESSION DURING DEVELOPMENT

Item 16 DIFFERENTIATION AND MATURATION OF THE NEURONAL LINEAGE

Item 17 NEURODEGENERATION AT THE CELLULAR LEVEL

Item 18 EMBRYOUS MODELS IN THE STUDY OF CELL MIGRATION

Item 19 EPITELIUM-MESENCHEME TRANSITION DURING DEVELOPMENT

Item 20 POLARIZATION AND ADHESION IN CELL MIGRATION DURING EMBRYONARY MORPHOGENESIS

Item 21 EMBRIONARY DEVELOPMENT OF BLOOD CELLS AND THE IMMUNITY SYSTEM

Item 22 EMBRYOUS DEVELOPMENT OF BLOOD VESSELS

Item 23 REGULATION AND ROLE OF CELL DEATH DURING EMBRIONARY DEVELOPMENT I

Item 24 REGULATION AND ROLE OF CELL DEATH DURING EMBRIONARY DEVELOPMENT II

Bibliography

Compulsory materials

For each individual subject included in the program the student will be provided by the instructors with additional teaching aids (i.e Power Point presentations and other specialized references as reviews or research articles).

Basic bibliography

1.- Cell biology. Thomas D. Pollard y william C. Earnshaw. Saunders

2.- Cell and Molecular Biology. Concepts and Experiments. Gerald Karp 3RD Ed. John Wiley and Sons,INC 3.- Physiological Basis of Aging and Geriatrics. Editado por P.S.Timiras CRC Press 2003

4.- Biogerontología. Editado por D.Crespo. Universidad de Cantabria 2006.

5.- Neuroscience. 2nd ed. Purves, Dale; Augustine, George.J.; Fitzpatrick, David; Katz, Lawrence.C.; LaMantia, Anthony-Samuel.;McNamara, James.O.; Williams, S. Mark, editors.Sunderland (MA): Sinauer Associates, Inc. c2001.(http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=neurosci)

6.-Basic Neurochemistry, Molecular, Cellular, and Medical Aspects 6th ed.

Siegal, George J.; Agranoff, Bernard W.; Albers, R. Wayne; Fisher, Stephen K.; Uhler, Michael D., editors.Philadelphia: Lippincott, Williams & Wilkins; c1999. (http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=bnchm)

7.- Developmental Biology. Eighth Edition. By Scott F. Gilbert Sinauer Aaasociated Eds

8.- Principles of development Lewis Wolpert, Rosa Beddington, Thomas Jessell, Peter Lawrence, Elliot Meyerowitz and Jim Smith. 2nd Ed. Oxford university press

In-depth bibliography

1.- Cell biology. Thomas D. Pollard y william C. Earnshaw. Saunders



2.- Cell and Molecular Biology. Concepts and Experiments. Gerald Karp 3RD Ed. John Wiley and Sons,INC



3.- Physiological Basis of Aging and Geriatrics. Editado por P.S.Timiras CRC Press 2003



4.- Biogerontología. Editado por D.Crespo. Universidad de Cantabria 2006.



5.- Neuroscience. 2nd ed. Purves, Dale; Augustine, George.J.; Fitzpatrick, David; Katz, Lawrence.C.; LaMantia, Anthony-Samuel.;McNamara, James.O.; Williams, S. Mark, editors.Sunderland (MA): Sinauer Associates, Inc. c2001.(http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=neurosci)



6.-Basic Neurochemistry, Molecular, Cellular, and Medical Aspects 6th ed.



Siegal, George J.; Agranoff, Bernard W.; Albers, R. Wayne; Fisher, Stephen K.; Uhler, Michael D., editors.Philadelphia: Lippincott, Williams & Wilkins; c1999. (http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=bnchm)



7.- Developmental Biology. Eighth Edition. By Scott F. Gilbert Sinauer Aaasociated Eds



8.- Principles of development Lewis Wolpert, Rosa Beddington, Thomas Jessell, Peter Lawrence, Elliot Meyerowitz and Jim Smith. 2nd Ed. Oxford university press

Links

Human Ageing Genomic Resources.http://genomics.senescence.info/ National institute of Aging.



American Society on Aging. http://www.asaging.org/index.cfm